Embedded droplet printing in yield-stress fluids

Proceedings of the National Academy of Sciences of the United States of America
Arif Z NelsonPatrick S Doyle

Abstract

Microfluidic tools and techniques for manipulating fluid droplets have become core to many scientific and technological fields. Despite the plethora of existing approaches to fluidic manipulation, non-Newtonian fluid phenomena are rarely taken advantage of. Here we introduce embedded droplet printing-a system and methods for the generation, trapping, and processing of fluid droplets within yield-stress fluids, materials that exhibit extreme shear thinning. This technique allows for the manipulation of droplets under conditions that are simply unattainable with conventional microfluidic methods, namely the elimination of exterior influences including convection and solid boundaries. Because of this, we believe embedded droplet printing approaches an ideal for the experimentation, processing, or observation of many samples in an "absolutely quiescent" state, while also removing some troublesome aspects of microfluidics including the use of surfactants and the complexity of device manufacturing. We characterize a model material system to understand the process of droplet generation inside yield-stress fluids and develop a nascent set of archetypal operations that can be performed with embedded droplet printing. With these principl...Continue Reading

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Citations

Jun 17, 2020·Proceedings of the National Academy of Sciences of the United States of America·Hing Jii MeaJiandi Wan
Nov 6, 2020·Lab on a Chip·Yuxin ZhangShi-Yang Tang
Jan 22, 2021·ACS Applied Materials & Interfaces·Mohammadreza MahmoudiMajid Minary-Jolandan
Feb 11, 2021·APL Bioengineering·Megan E Cooke, Derek H Rosenzweig
Jul 24, 2021·Soft Matter·Leanne M Friedrich, Jonathan E Seppala
Nov 11, 2020·Analytical Chemistry·Simon F BerlandaPetra S Dittrich

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Methods Mentioned

BETA
rheology
scanning electron microscopy
X-ray
differential
transmission electron microscopy
confocal microscopy

Software Mentioned

Repetier
Origin
Toolbox of Embedded Droplet Printing
ImageJ

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