Embolization in the palliation of complications of inoperable primary pancreatic neoplasms

Clinical Radiology
M KhoursheedD A Gould

Abstract

Primary pancreatic neoplasm typically presents at an advanced stage where surgical management may not be feasible. These patients are often symptomatic due to biliary obstruction but problems may also include gastrointestinal bleeding and endocrinological complications. We describe two cases illustrating the use of palliative embolization in the control of biochemical and haemorrhagic complications of primary pancreatic neoplasm. In one case, massive gastrointestinal bleeding from an inoperable primary pancreatic carcinoma was controlled by two embolization procedures to produce devascularization of the primary lesion. In a second case, life-threatening hypercalcaemia was thought to be due to secretion of a parathormone-like material from an inoperable islet cell tumour. There was no evidence of liver metastases and the pancreatic mass was embolized, following which serum calcium was reduced to near normal levels with considerable clinical improvement. We conclude that there is a role for embolization of inoperable primary pancreatic neoplasm in the palliation of biochemical or haemorrhagic complications of these tumours.

References

Jan 1, 1992·Gastrointestinal Radiology·M OkazakiS Furui
Nov 1, 1992·Journal of Vascular and Interventional Radiology : JVIR·R Uflacker
Oct 1, 1983·British Medical Journal·P N MatonV S Chadwick
Jul 1, 1993·Journal of Vascular and Interventional Radiology : JVIR·F BoudghèneJ M Bigot
Feb 1, 1993·The Journal of Surgical Research·D B AdamsM C Anderson

❮ Previous
Next ❯

Citations

Oct 30, 2012·Journal of Vascular and Interventional Radiology : JVIR·Daniel J TandbergCharles Y Kim

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adenoma, Islet Cell

Islet Cell Adenoma arises in the islet cells, which are insulin producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on Islet Cell Adenoma here.

Carcinoma, Islet Cell

Islet Cell Carcinoma or Pancreatic Neuroendocrine Tumours arises in the hormone producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on Islet Cell Carcinoma here.

Carcinoma, Islet Cell (Keystone)

Islet Cell Carcinoma or Pancreatic Neuroendocrine Tumours arise in the hormone producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on islet cell carcinoma in this feed.