PMID: 11334300May 4, 2001Paper

Embolization of arteriovenous malformations with Onyx: clinicopathological experience in 23 patients

Neurosurgery
R JahanFernando Viñuela

Abstract

To report our experience in treatment of arteriovenous malformations (AVMs) using a new liquid embolic agent, Onyx (Micro Therapeutics, Inc., Irvine, CA). Between January 1998 and May 1999, 23 patients (8 men and 15 women) were treated. The patients' average age was 40 years, with seizure being the most common presenting symptom (39%). The average Spetzler-Martin grade on presentation was 3. The average AVM volume before embolization was 14.5 cm3. We observed an average 63% reduction in AVM volume after 129 arterial feeders were embolized. There were four adverse events. Two patients experienced ischemia because of inadvertent occlusion of an arterial feeder. One of these patients made a full recovery, but the other patient had a permanent deficit. Two other patients experienced transient neurological deficits that resolved within 1 week of embolization. Permanent morbidity was thus 4% (1 of 23 patients). There were no deaths. Twelve patients underwent subsequent radiosurgery, and 11 patients had surgery that resulted in complete resection of their AVMs. Histopathological examinations showed mild acute inflammation in specimens resected 1 day after embolization. Chronic inflammatory changes were observed in specimens resected m...Continue Reading

References

Feb 20, 1986·The New England Journal of Medicine·H V VintersJ C Kaufmann
Oct 1, 1986·Journal of Neurosurgery·R F Spetzler, N A Martin
Sep 1, 1980·Radiology·C ZollikoferK Amplatz
Jan 1, 1995·British Journal of Neurosurgery·S A O'Laoire
Jul 1, 1996·Journal of Neurosurgery·Y P GobinJ J Merland

❮ Previous
Next ❯

Citations

Feb 10, 2006·Neurosurgical Focus·A R DehdashtiD A Ruefenacht
Aug 19, 2007·AJNR. American Journal of Neuroradiology·A AratY O Arat
Nov 8, 2008·AJNR. American Journal of Neuroradiology·M Jayaraman, H J Cloft
Dec 30, 2008·AJNR. American Journal of Neuroradiology·E F HauckD Samson
Jan 25, 2012·Pediatric Surgery International·Murat CantasdemirFuruzan Numan
Sep 6, 2012·Journal of Korean Neurosurgical Society·Jae Il LeeTae Hong Lee
Jun 5, 2014·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·H PulhornD N P Thompson
May 4, 2015·Journal of Neurointerventional Surgery·Caterina MichelozziChristophe Cognard
Jun 17, 2005·Cardiovascular and Interventional Radiology·Olivier JordanDaniel A Rüfenacht
Oct 17, 2006·Neurosurgery·Ricardo J KomotarPhilip M Meyers
Oct 10, 2008·AJNR. American Journal of Neuroradiology·V PanagiotopoulosI Wanke
Jun 21, 2011·Critical Care Research and Practice·Isaac TawilChristopher L Taylor
Nov 20, 2016·Science Translational Medicine·Reginald K AveryRahmi Oklu
Feb 7, 2007·Expert Review of Medical Devices·Michael AyadRobert A Mericle
May 13, 2004·Journal of Neurosurgery·Christopher L TaylorDuke S Samson
Oct 24, 2006·AJR. American Journal of Roentgenology·Peter P RiveraStephen P Lownie
Mar 17, 2009·Journal of Neurosurgery·Zhong-Song ShiFernando Viñuela
Jul 31, 2013·Expert Review of Medical Devices·Jalal JalalyShaker A Mousa
Aug 14, 2012·Acta Neurologica Scandinavica·G Rodríguez-BotoL López-Ibor
Jan 16, 2014·The Indian Journal of Surgery·Arindam Bharadwaz, Gayatri Madhab
Dec 21, 2018·Journal of Neurointerventional Surgery·Raoul PopRémy Beaujeux
Sep 12, 2020·Clinical Neuroradiology·Mayank GoyalJohanna Maria Ospel
Sep 15, 2009·AJNR. American Journal of Neuroradiology·R ThiexD B Orbach
Mar 5, 2019·Advanced Healthcare Materials·Daniel CohnRaju Ramanujan
Nov 3, 2007·AJNR. American Journal of Neuroradiology·R G NogueiraJ C Pryor

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.