PMID: 24358512Dec 21, 2013Paper

Embryo gene expression in response to maternal supplementation with glycogenic precursors in the rabbit

Animal Reproduction Science
M Arias-AlvarezP G Rebollar

Abstract

Disturbing maternal metabolism during the first pregnancy and postpartum period is associated with sub fertility in rabbit does. Nutritional strategies can be used during those periods and its effects to improve reproductive management may affect periconceptional events and early embryo development. Our goal was to elucidate if treatment with a glycogenic precursor such as propylene glycol (PG) could affect the maternal metabolic profile, follicular and oocyte quality and gene expression patterns in early embryos. Rabbit does were supplemented with 2.5% (v/v) PG from either mid-pregnancy and for 25 days of lactation (PG-GL group); only during lactation (PG-L group); or were not treated (control group). Ovarian parameters and embryos were studied at the end of treatment. At parturition serum non-esterified fatty acid concentrations increased whilst insulin decreased in all groups. Maternal feed intake was reduced in PG-supplemented does but glycaemia was maintained during the experimental period. When PG was suppressed, blood insulin immediately increased in PG-groups, but no differences in follicular population, follicular atresia, and nuclear and cytoplasmic oocyte maturation were observed compared with non-treated animals. Al...Continue Reading

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Citations

Oct 4, 2014·Reproduction in Domestic Animals = Zuchthygiene·P L LorenzoP G Rebollar
May 11, 2018·Molecular Reproduction and Development·Denise LaskowskiGöran Andersson

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