PMID: 9193725Jun 1, 1997Paper

Embryonic and postnatal development of the rat renal interstitium

Anatomy and Embryology
C MaricD Alcorn

Abstract

Whilst antihypertensive, structural and functional roles have been proposed for the cells of the renomedullary interstitium in the adult kidney, little is known about its role in renal development. Rat kidneys were studied throughout development, prenatally at gestational ages E14-E21 and postnatally at 0-28 days, by light microscopy, transmission and scanning electron microscopy and following immunocytochemistry. Renomedullary interstitial cells were observed as early as embryonic day E14, forming a loose, orderly network around branches of the ureteric bud. Paralleling the development of the first nephron structures, renomedullary interstitial cells were arranged in a concentric circular manner around collecting ducts. Following tubular and vascular growth from the cortex into the medulla, this arrangement resulted in the characteristic 'rungs of a ladder' appearance of interstitial cells between tubules, blood vessels and the collecting ducts. Renomedullary interstitial cells were closely adherent to basement membranes of tubules, blood vessels and collecting ducts from early in development. Contacts were absent between renomedullary interstitial cells and tubular structures in the process of remodelling, such as the hair-pi...Continue Reading

Citations

Aug 9, 2011·Histochemistry and Cell Biology·Will W MinuthAnne Glashauser
Jan 8, 2005·Nephron. Experimental Nephrology·Luise A Cullen-McEwenJohn F Bertram
Oct 3, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Marco PiluduGavino Faa
Jul 23, 2014·Clinical and Experimental Hypertension : CHE·Pavel SvitokMichal Zeman
Feb 11, 2005·Clinical and Experimental Hypertension : CHE·Marcus BaumannHarry A J Struijker-Boudier
May 14, 2011·Gene Expression Patterns : GEP·Taro KitazawaHiroki Kurihara
Jul 14, 2006·Clinical Physiology and Functional Imaging·Daina LasaitienePeter Friberg
Apr 27, 2013·Journal of Applied Toxicology : JAT·Shino Homma-TakedaYoshiya Shimada
Feb 6, 2010·Cancer Science·Toshiaki KokuboYoshiya Shimada
Mar 2, 2017·Cold Spring Harbor Perspectives in Biology·Joan Seoane, Roger R Gomis
Jul 31, 2007·Nature Medicine·Elisabeth M ZeisbergRaghu Kalluri
Aug 16, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Sunghou LeeChristine Maric
Mar 6, 2003·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Shiying CuiSusan E Quaggin
Apr 21, 2021·Journal of the American Society of Nephrology : JASN·Sarah N LippSarah Calve

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