Embryonic health: new insights, mHealth and personalised patient care

Reproduction, Fertility, and Development
Régine P M Steegers-Theunissen, Eric A P Steegers

Abstract

The worldwide epidemic of non-communicable diseases (NCD), including obesity, is a burden to which poor lifestyles contribute significantly. Events in early life may enhance susceptibility to NCD, with transmission into succeeding generations. This may also explain, in part, why interventions in adulthood are less effective to reduce NCD risk. New insights reveal that the early embryo, in particular, is extremely sensitive to signals from gametes, trophoblastic tissue and periconception maternal lifestyles. Embryonic size and growth as determinants of embryonic health seem to impact future health. A relatively small embryo for gestational age is associated with pregnancy complications, as well as with the risk of early features of NCD in childhood. Although personal lifestyles are modifiable, they are extremely difficult to change. Therefore, adopting a life course approach from the periconception period onwards and integrated into patient care with short-term reproductive health benefits may have important implications for future prevention of NCD. The current reproductive population is used to Internet and social media. Therefore, they can be reached via mobile phone (mHealth) platforms that provide personalised lifestyle (pr...Continue Reading

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Citations

Feb 11, 2016·Paediatric and Perinatal Epidemiology·Eric A P SteegersMichelle A Williams
May 29, 2016·JMIR MHealth and UHealth·Matthijs R Van DijkRégine Pm Steegers-Theunissen
May 31, 2016·Journal of Reproductive Immunology·Emilie M HerzogRegine P M Steegers-Theunissen
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Jan 13, 2017·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·F ParisiR P M Steegers-Theunissen
Nov 20, 2018·The Journal of Obstetrics and Gynaecology Research·Hein BogersEric A P Steegers
Nov 5, 2020·The Journal of Obstetrics and Gynaecology Research·Anne FrudigerEric A P Steegers

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Methods Mentioned

BETA
imaging techniques

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