Embryonic hypoxia programmes postprandial cardiovascular function in adult common snapping turtles (Chelydra serpentina )

The Journal of Experimental Biology
Oliver H WearingDane A Crossley

Abstract

Reduced oxygen availability (hypoxia) is a potent stressor during embryonic development, altering the trajectory of trait maturation and organismal phenotype. We previously documented that chronic embryonic hypoxia has a lasting impact on the metabolic response to feeding in juvenile snapping turtles (Chelydra serpentina). Turtles exposed to hypoxia as embryos [10% O2 (H10)] exhibited an earlier and increased peak postprandial oxygen consumption rate, compared with control turtles [21% O2 (N21)]. In the current study, we measured central blood flow patterns to determine whether the elevated postprandial metabolic response in H10 turtles is linked to lasting impacts on convective transport. Five years after hatching, turtles were instrumented to quantify systemic ([Formula: see text]) and pulmonary ([Formula: see text]) blood flows and heart rate (fH) before and after a ∼5% body mass meal. In adult N21 and H10 turtles, fH was increased significantly by feeding. Although total stroke volume (VS,tot) remained at fasted values, this tachycardia contributed to an elevation in total cardiac output ([Formula: see text]). However, there was a postprandial reduction in a net left-right (L-R) shunt in N21 snapping turtles only. Relative ...Continue Reading

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Citations

Sep 16, 2018·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·William JoyceDane A Crossley
Jan 23, 2018·Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology·Gerardo A CorderoFabien Aubret
Apr 21, 2019·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Renato Filogonio, Dane A Crossley
May 14, 2021·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·John EmeDane A Crossley

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