Emergence delirium in children is not related to intraoperative burst suppression - prospective, observational electrography study

BMC Anesthesiology
Susanne KochClaudia D Spies

Abstract

Emergence-delirium is the most frequent brain dysfunction in children recovering from general anaesthesia, though the pathophysiological background remains unclear. The presented study analysed an association between emergence delirium and intraoperative Burst Suppression activity in the electroencephalogram, a period of very deep hypnosis during general anaesthesia. In this prospective, observational cohort study at the Charité - university hospital in Berlin / Germany children aged 0.5 to 8 years, undergoing planned surgery, were included between September 2015 and February 2017. Intraoperative bi-frontal electroencephalograms were recorded. Occurrence and duration of Burst Suppression periods were visually analysed. Emergence delirium was assessed using the Pediatric Assessment of Emergence Delirium Score. From 97 children being analysed within this study, 40 children developed emergence delirium, and 57 children did not. Overall 52% of the children displayed intraoperative Burst Suppression periods; however, occurrence and duration of Burst Suppression (Emergence delirium group 55% / 261 + 462 s vs. Non-emergence delirium group 49% / 318 + 531 s) did not differ significantly between both groups. Our data reveal no correlati...Continue Reading

Associated Clinical Trials

References

Dec 31, 2010·The New England Journal of Medicine·Emery N BrownNicholas D Schiff
Oct 3, 2012·Journal of Neurosurgical Anesthesiology·Matthew T V ChanUNKNOWN CODA Trial Group
Sep 3, 2013·Lancet·Sharon K InouyeJane S Saczynski
Jan 15, 2014·Anesthesia and Analgesia·Elizabeth L WhitlockMichael S Avidan
May 3, 2014·Current Opinion in Anaesthesiology·Souhayl DahmaniJulie Hilly
Sep 30, 2015·Anesthesia and Analgesia·Bradley A FritzMichael S Avidan
Jan 16, 2016·Anesthesia and Analgesia·Heather J FrederickScott R Schulman
Nov 2, 2016·Journal of Intensive Care·Abigail Glicksman KersonChani Traube

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Citations

Sep 13, 2021·Paediatric Anaesthesia·Emmett E WhitakerRobert K Williams

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Methods Mentioned

BETA
sedation

Clinical Trials Mentioned

NCT02481999
NCT02358278

Software Mentioned

SPSS
EEG viewer

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