Emergence from isoflurane/N2O or isoflurane anaesthesia

Acta Anaesthesiologica Scandinavica
S EinarssonJ P Bengtson

Abstract

The first goal of anaesthetic recovery is return of the patient's ability to independently maintain respiratory and circulatory functions. Nitrous oxide remains popular due to minor effects on the cardiovascular and respiratory systems. However, diffusion hypoxaemia can occur during recovery and there is a potential advantage of providing the patient with only a potent vaporised agent. This randomised study of 20 gynaecological patients evaluated respiratory and circulatory variables during emergence after anaesthesia with equipotent mixtures of isoflurane/nitrous oxide or isoflurane. Inspired, end-tidal and mixed expired gas concentrations, expired minute volume, pulse oximetry saturation and arterial blood gases were registered. Monitoring of cardiac output was performed by transthoracic bioimpedance. Patients anaesthetised with isoflurane/N2O resumed their spontaneous breathing 16 min earlier and were extubated 22 min earlier than those anaesthetised with only isoflurane. At extubation, total MAC and end-tidal CO2 were similar in both groups, 0.22-0.26 and 5.5-5.9 vol%, respectively. The isoflurane/ N2O group had greater minute ventilation and CO2 excretion rates than the isoflurane group throughout the emergence period. The...Continue Reading

References

Apr 1, 1992·Anesthesia and Analgesia·R HinesT O'Connor
Oct 1, 1988·Acta Anaesthesiologica Scandinavica·J P BengtsonO Stenqvist
Nov 1, 1988·Acta Anaesthesiologica Scandinavica·J P VialeJ Motin
Jul 1, 1971·Anesthesiology·H E FourcadeE I Eger
Nov 1, 1983·Canadian Anaesthetists' Society Journal·R L KnillJ L Clement
Jul 1, 1982·Anesthesia and Analgesia·T F HornbeinK H Smith
Jan 1, 1995·Acta Anaesthesiologica Scandinavica·D SjögrenS G Lindahl
Jan 1, 1995·Acta Anaesthesiologica Scandinavica·K NishinaH Obara
Aug 1, 1993·British Journal of Anaesthesia·S EinarssonJ P Bengtson
May 1, 1994·British Journal of Anaesthesia·N W Goodman
May 1, 1993·Anesthesiology·A I McEwanP S Glass
Jul 1, 1955·Anesthesiology·B R FINK

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Citations

May 8, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·S EinarssonJ P Bengtson
Oct 3, 2006·Current Opinion in Anaesthesiology·M F James
Feb 10, 2009·The Journal of Small Animal Practice·S LaingP J Murison

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