Emergence of a single clone of community-associated methicillin-resistant Staphylococcus aureus in southern Madrid children

Enfermedades infecciosas y microbiología clínica
Amparo BrosetaJoaquín R Otero

Abstract

The observation of an increasing number of methicillin-resistant Staphylococcus aureus (MRSA) isolated from children prompted us to study the microbiological, epidemiological and clinical characteristics of these isolates. The possibility of some of them being community-acquired focused particularly our attention. A retrospective analysis of all children with MRSA isolated at the Doce de Octubre hospital between January 2002 and June 2005 was conducted. Infections were classified as community-acquired, hospital-acquired, or health-care associated. Isolates of MRSA were studied by pulsed-field gel electrophoresis (PFGE) and SSCmec typing. The presence of the gene encoding the Panton-Valentine leukocidin was also detected by PCR. MRSA were isolated from 17 patients. Seven isolates (42.2%) were community-acquired, corresponding to four cases of skin or soft-tissue infections, two otitis cases and one bacteremic pyomyositis. Six of seven community-acquired isolates had the same ECP pattern (genotype D), presented a type IV SSCmec, and were LPV toxin-producing and methicillin-resistant with no other associated resistances. To our knowledge, this study shows the presence of these community-acquired MRSA strains for the first time in ...Continue Reading

Citations

Jun 10, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·I NiniouM N Tsolia
Jul 6, 2014·The Journal of Antimicrobial Chemotherapy·Ana VindelEmilia Cercenado
May 12, 2010·Expert Review of Anti-infective Therapy·Pablo RojoFernando Chaves
Jul 26, 2011·Influenza and Other Respiratory Viruses·Teresa del RosalMaría E Cabezas
Jan 1, 2021·Infection and Drug Resistance·Teresa Del RosalUNKNOWN COSACO Study Group
Jul 23, 2021·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·Lucía Garriga Ferrer-BerguaUNKNOWN en representación del Grupo de Trabajo de Enfermedades Infecciosas de la SEUP
Jul 1, 2008·Enfermedades infecciosas y microbiología clínica·Marta BarriosFernando Chaves

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