Emergence of blaNDM-5 in Enterobacteriaceae Isolates from Companion Animals in Guangzhou, China.

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Jing WangZhen-Ling Zeng

Abstract

The occurrence and characterization of carbapenemase-producing Enterobacteriaceae from companion animals in Guangzhou, China, are investigated. Six isolates (2.3%, 6/257) were positive for blaNDM-5, that is, one Enterobacter cloacae, one Citrobacter freundii, and four Escherichia coli. Three E. coli isolates obtained from the same animal hospital were ST410 and showed identical pulse field gel electrophoresis pattern, resistance profiles, and resistance genes. blaNDM-5 was located on IncX3 (n = 5) and IncK2 (n = 1) plasmid, respectively. The presence of carbapenemase-producing Enterobacteriaceae among companion animals needs continued surveillance.

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Datasets Mentioned

BETA
KU167608
MF547508
MN276078
MN276083

Methods Mentioned

BETA
PCR
electrophoresis

Software Mentioned

ResFinder
BLAST
RAST
SOAPdenovo
ISfinder

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