Emergence of IncX4 plasmids encoding mcr-1 in a clinical isolate of Klebsiella pneumoniae in Japan

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Tatsuya TadaJiro Fujita

Abstract

The mcr-1 gene encodes a phosphoethanolamine transferase that confers resistance to colistin by transferring phosphoethanolamine to lipid A. A 33-kb IncX4 plasmid harboring mcr-1 was detected in a Klebsiella pneumoniae isolate and two Escherichia coli isolates, and a 66-kb IncI2 plasmid was detected in three E. coli isolates in hospitals in Okinawa, Japan.

Citations

Jun 10, 2020·The Journal of Antimicrobial Chemotherapy·Jiayue LuRong Zhang
Apr 10, 2021·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Wataru HayashiNoriyuki Nagano
Jun 29, 2021·Frontiers in Microbiology·Raquel GirardelloJoão Carlos Setubal

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