Emergence of multiple-antibiotic-resistant Streptococcus pneumoniae in Hong Kong.

Antimicrobial Agents and Chemotherapy
K M KamM M Cheung

Abstract

Two hundred four strains of Streptococcus pneumoniae isolated in Hong Kong from January 1993 to May 1995 were analyzed for their antibiotic susceptibilities and epidemiological patterns. The ages of the patients from whom the strains were isolated from 1 month to 93 years (median, 53 years); the male-to-female ratio was 2.8, with a predominance of males in the pediatric group. Fifty-nine (28.9%) strains showed reduced penicillin susceptibility, including 40 (19.6%) with frank penicillin resistance (MIC > 1 microgram/ml). Tetracycline resistance alone was found in 28.4% of strains. Isolates with reduced penicillin susceptibility were more common in children than adults (40 versus 23.9%, P = 0.02), and penicillin resistance rates were significantly higher in hospitalized patients than in outpatients (39.5 versus 12.5%; p < 0.001). Penicillin resistance was significantly associated with resistance to ceftriaxone, erythromycin, and tetracycline (P < 0.01) but not with ofloxacin or vancomycin (P = 0.5). Among eight different patterns of resistance to three or more antibiotics, the commonest one (14.2%) was multiple resistance to penicillin, chloramphenicol, ceftriaxone, erythromycin, and tetracycline. Emergence of multiple-antibioti...Continue Reading

References

Dec 16, 1992·JAMA : the Journal of the American Medical Association·R DaganD ] Englehard D [corrected to Engelhard
Nov 1, 1992·Archives of Internal Medicine·M M CorteseM Santosham
Apr 1, 1992·Antimicrobial Agents and Chemotherapy·K P FuM E Rosenthale
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A Marton
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P C Appelbaum
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P GeslinJ F Acar
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J LiñaresR Martin
Mar 1, 1991·The Pediatric Infectious Disease Journal·J AlonsoM García-Fuentes
Dec 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E Pérez-TralleroA Peris
Jun 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J VerhaegenJ Vandepitte
Dec 1, 1989·The Pediatric Infectious Disease Journal·F AsensiE Cantó
Apr 1, 1986·The Journal of Antimicrobial Chemotherapy·A King, I Phillips
Nov 1, 1986·The Journal of Antimicrobial Chemotherapy·S RaoofF Khan
Oct 1, 1985·The Journal of Antimicrobial Chemotherapy·E E Ligtvoet, T Wickerhoff-Minoggio
Apr 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·H J LeeK W Choi
Feb 1, 1994·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C C John
Feb 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D N TsangK C Lee
Mar 1, 1993·The Pediatric Infectious Disease Journal·I R FriedlandG H McCracken

❮ Previous
Next ❯

Citations

Mar 25, 1998·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·R Dagan
Nov 24, 1999·International Journal of Antimicrobial Agents·L LatiniR Ronchetti
Oct 18, 2002·The Lancet Infectious Diseases·Ron Dagan, Eugene Leibovitz
Oct 29, 1997·Proceedings of the National Academy of Sciences of the United States of America·S BonhoefferB R Levin
Apr 26, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D J HobanR N Jones
Jan 26, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Clyde ThornsberryJames A Karlowsky
Jan 26, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph P Lynch III, Fernando J Martinez
Jan 1, 1996·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·C CatchpoleR Wise
Oct 1, 1996·The Pediatric Infectious Disease Journal·P C Appelbaum
Dec 13, 2006·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Jamshid Kohanteb, Esmaeel Sadeghi
Sep 1, 2009·Molecular Simulation·Abdallah Sayyed-AhmadYiannis N Kaznessis
Jan 1, 1996·Scandinavian Journal of Infectious Diseases·D J LyonJ Henrichsen
Apr 2, 2002·Expert Opinion on Investigational Drugs·Francesco BlasiPaolo Tarsia
Jun 23, 2009·Vaccine·M Teresa Valenzuela, Ciro de Quadros
May 2, 2000·Journal of Chemotherapy·A M ShiblA O Osoba
Jan 1, 1997·Antimicrobial Agents and Chemotherapy·E L FasolaM R Jacobs

❮ Previous
Next ❯

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