Emergence of multiple drug-resistant human cytomegalovirus variants in 2 patients with human immunodeficiency virus infection unresponsive to highly active antiretroviral therapy

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
F BaldantiG Gerna

Abstract

In 2 patients infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy was unable to suppress HIV replication as a result of the emergence of drug-resistant HIV variants. Human cytomegalovirus (HCMV) retinitis developed in both patients, and an unusually complex mixture of drug-resistant HCMV variants was detected in both patients.

References

Apr 16, 1998·The New England Journal of Medicine·S M Levitz
Dec 20, 2000·The Journal of Infectious Diseases·D A JabsUNKNOWN Cytomegalovirus Retinitis and Viral Resistance Study Group

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Citations

Mar 17, 2004·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Alexandra DucancelleMarie-Christine Mazeron
Feb 25, 2005·Antimicrobial Agents and Chemotherapy·C Gilbert, G Boivin
Oct 12, 2010·Clinical Microbiology Reviews·Nell S Lurain, Sunwen Chou
Mar 5, 2004·Survey of Ophthalmology·Tamara R Vrabec
Oct 27, 2009·Antiviral Research·Meike ChevillotteThomas Mertens

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