Emergence of new genotype and diversity of Theileria orientalis parasites from bovines in India

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases
Neena GeorgeParesh Sharma

Abstract

Bovine theileriosis is a serious threat to livestock worldwide. Uncertainty around species prevalence, antigenic diversity and genotypes of strains make it difficult to assess the impact of this parasite and to provide necessary treatment. We aimed to characterize genotypic diversity, phylogeny and prevalence of Theileria orientalis parasites from the states of Telangana and Andhra Pradesh, India by collecting bovine blood samples from the major districts of the two states. Bioinformatic analysis identified antigenic diversity among the prevalent parasite strains using major piroplasm surface protein (MPSP) gene. Our study revealed a prevalence rate of 4.8% (n=41/862) of T. orientalis parasites in bovine animals and a new genotype of T. orientalis parasite which was not previously reported in India. The emergence of these new genotypes could be an explanation for the frequent outbreaks of bovine theileriosis. Further, whole genome sequencing of T. orientalis strains will help to elucidate the genetic factors relevant for transmissibility and virulence as well as vaccine and new drug development.

References

Jul 29, 1998·Comparative Immunology, Microbiology and Infectious Diseases·M OnumaC Sugimoto
Aug 5, 2009·The Journal of Veterinary Medical Science·Naomi OtaNaoaki Yokoyama
Oct 28, 2010·The Journal of Veterinary Medical Science·Naoaki YokoyamaHisashi Inokuma
Jan 22, 2013·Ticks and Tick-borne Diseases·Thillaiampalam SivakumarNaoaki Yokoyama
Oct 18, 2013·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
May 3, 2014·Parasitology International·Saw BawmKen Katakura
Aug 8, 2014·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Thillaiampalam SivakumarNaoaki Yokoyama
Feb 24, 2015·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·Anisha TiwariS S Rath

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