Emergency corneal grafting in the UK: a 6-year analysis of the UK Transplant Registry

The British Journal of Ophthalmology
Parwez HossainNHS Blood and Transplant Ocular Tissue Advisory Group and Contributing Ophthalmologists

Abstract

Corneal graft (CG) surgery is the most common and successful tissue transplant worldwide. A small and important group of patients are operated in emergency situations, typically to save a perforated eye. Our knowledge of the indications and outcomes of emergency corneal graft (eCG) is limited. Retrospective, multifactorial analysis of all CGs registered by the UK Transplant Service from April 1999 to March 2005. A total of 12 976 CGs were performed. 1330 (11.4%) were eCGs including 433 regrafts. Actual perforation occurred in 876 (65.9%) patients. 420 (31.5%) grafts were for tectonic purposes alone and 217 (16.3%) were also grafted for visual rehabilitation. The main diagnostic categories were infection (39.4%), non-infectious ulcerative keratitis (32.2%) and other causes (ectasias, previous ocular surgery, injury, dystrophies and opacification). Graft survival of first eCG at 1, 2 and 5 years was 78%, 66% and 47%, respectively. Best-corrected visual acuity of surviving grafts at 1 year was: 6/12 or better in 29.9%, 6/18 to 6/60 in 38.4%, counting finger to LP in 30.6% and NPL in 1%, with worsening of vision in only 8.7% of the patients. This study which is the largest of its kind shows that despite the seriousness of the criti...Continue Reading

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Citations

May 1, 2018·Current Opinion in Ophthalmology·Sonal TuliAnkit Shah
Jun 1, 2018·Journal of Ophthalmology·Katarzyna KrysikDariusz Dobrowolski
Jun 23, 2021·Scientific Reports·Darren Shu Jeng TingHarminder S Dua
May 4, 2021·Cornea·Alfonso Vasquez-PerezBruce Allan

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