PMID: 11334200May 4, 2001Paper

Emergency redo mitral valve replacement in a 27-year-old pregnant female with a clotted prosthetic mitral valve, preoperative fetal demise and postoperative ventricular assist device: a case report

Perfusion
D OlesM A Bhatti

Abstract

A 27-year-old Laotian woman with a St Jude mechanical mitral valve became pregnant, requiring a change in her anticoagulant after the first trimester when her warfarin sodium (coumadin) was replaced with enoxaparin sodium (lovenox). Her prosthetic valve clotted and became dysfunctional. She was 16 weeks pregnant and was taken to the operating room for emergency surgery for replacement of the valve. The fetus had not been viable for 1-2 weeks, but still remained in utero. The clotted valve was replaced with another St Jude valve of a slightly smaller diameter (27 mm). The patient could not be weaned from bypass so a right ventricular assist device (RVAD) was inserted. The patient was weaned from the RVAD after 2 days of support. Two days following removal of the RVAD the fetus spontaneously aborted. The patient had a long, complicated hospital course and was discharged 3 months later. She subsequently died 4 months after discharge of a cerebral hemorrhage from excessive anticoagulation.

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Citations

Jul 25, 2007·Annals of Cardiac Anaesthesia·Aseem R SrivastavaAmit Banerjee
Sep 13, 2006·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Andra H JamesThomas L Ortel
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Jan 29, 2013·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·David FeldmanUNKNOWN International Society for Heart and Lung Transplantation
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Dec 21, 2005·Perfusion·Steven W SuttonRichard E Wood

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