Emerging epidemic of drug-resistant tuberculosis in Europe, Russia, China, South America and Asia: current status and global perspectives

Current Opinion in Pulmonary Medicine
G B MiglioriG Sotgiu

Abstract

Drug resistance, particularly through multidrug-resistant tuberculosis (TB) and extensively drug-resistant TB strains, poses a real threat to TB control worldwide. Recent reports from the WHO and the International Union Against Tuberculosis and Lung Disease demonstrate that the emerging epidemic of drug-resistant TB is a global problem, although emphasis has been placed on several 'hot spots' because of lack of good global data. The present article is aimed at reviewing the available information on drug-resistant TB with special focus on the features of the epidemic in Europe, Russia, Latin America, Asia and specifically China, and to discuss the global perspectives related to drug-resistant TB control and care. Drug-resistant TB originates from different human errors, including misuse of anti-TB drugs and other reasons related to prescribers, patients and drug producers. Although there is an urgent need for new drugs, a sound public health approach is necessary for their introduction in clinical treatment settings to prevent/avoid creating additional resistance, as has already been observed for first and second-line anti-TB drugs in many settings.

Citations

Dec 17, 2011·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Yusuke SakaiHiroyuki Nakayama
Nov 22, 2011·Revue des maladies respiratoires·J-P Zellweger
Mar 17, 2016·Osong Public Health and Research Perspectives·Fereshteh BadieSoodabeh S Gharibvand
Jun 16, 2010·Tropical Medicine & International Health : TM & IH·Giovanni Battista MiglioriAlimuddin Zumla
Jul 2, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Viviana RitaccoSofia Samper

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