Emerging epidemic viral encephalitides with a special focus on henipaviruses.

Acta Neuropathologica
K T Wong

Abstract

In the last few decades, there is an increasing emergence and re-emergence of viruses, such as West Nile virus, Enterovirus 71 and henipaviruses that cause epidemic viral encephalitis and other central nervous system (CNS) manifestations. The mortality and morbidity associated with these outbreaks are significant and frequently severe. While aspects of epidemiology, basic virology, etc., may be known, the pathology and pathogenesis are often less so, partly due to a lack of interest among pathologists or because many of these infections are considered "third world" diseases. In the study of epidemic viral encephalitis, the pathologist's role in unravelling the pathology and pathogenesis is critical. The novel henipavirus infection is a good example. The newly created genus Henipavirus within the family Paramyxoviridae consists of two viruses, viz., Hendra virus and Nipah virus. These two viruses emerged in Australia and Asia, respectively, to cause severe encephalitides in humans and animals. Studies show that the pathological features of the acute encephalitis caused by henipaviruses are similar and a unique dual pathogenetic mechanism of vasculitis-induced microinfarction and parenchymal cell infection in the CNS (mainly neur...Continue Reading

References

Apr 1, 1972·Journal of Neurology, Neurosurgery, and Psychiatry·M DonnerA L Saukkonen
Jun 19, 1995·The Medical Journal of Australia·L A SelveyJ W Sheridan
Apr 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·T Somer, S M Finegold
Jan 11, 1997·Lancet·J D O'SullivanJ Bradfield
Feb 11, 1999·Australian Veterinary Journal·M M WilliamsonP K Murray
Mar 25, 1999·The Journal of Infection·J G McCormackP W Selleck
Jul 3, 1999·Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada
Sep 25, 1999·The New England Journal of Medicine·C C HuangT F Yeh
Sep 29, 1999·Veterinary Microbiology·K HalpinJ S Mackenzie
Apr 27, 2000·The New England Journal of Medicine·K J GohS K Lam
May 24, 2000·The Journal of Infectious Diseases·M H ChewL J Anderson
Jul 19, 2000·The Journal of General Virology·K HalpinJ S Mackenzie
Aug 1, 2000·AJR. American Journal of Roentgenology·S A SarjiK T Wong
Aug 10, 2000·Neuropathology and Applied Neurobiology·K T Wong
Jan 2, 2001·Neuropathology : Official Journal of the Japanese Society of Neuropathology·S JogaiA K Banerjee
Feb 22, 2001·The Journal of Infectious Diseases·A W MountsUNKNOWN Nipah Virus Nosocomial Study Group
Feb 24, 2001·Revue Scientifique Et Technique·M N Mohd NorB L Ong
May 4, 2001·Microbes and Infection·B T Eaton
May 4, 2001·Microbes and Infection·A D HyattS G Hengstberger
May 24, 2001·Archives of Pathology & Laboratory Medicine·B K Kleinschmidt-DeMasters, D H Gilden
Oct 27, 2001·The Journal of Infectious Diseases·C T Tan, K S Tan
Nov 2, 2001·International Journal of Epidemiology·M SahaniUNKNOWN Nipah Encephalitis Outbreak Investigation Group
Mar 7, 2002·Microbes and Infection·Kaw Bing ChuaSai Kit Lam
Apr 12, 2002·Journal of Comparative Pathology·D J MiddletonA D Hyatt
Jul 12, 2002·Annals of Neurology·Chong Tin TanMohd Rani Jusoh
Aug 27, 2002·Emerging Infectious Diseases·James G OlsonThomas G Ksiazek
Dec 6, 2002·The American Journal of Pathology·Kum Thong WongUNKNOWN Nipah Virus Pathology Working Group
Dec 28, 2002·Springer Seminars in Immunopathology·K T WongC T Tan
Oct 28, 2003·The American Journal of Pathology·K Thong WongVincent Deubel
Dec 24, 2004·The Journal of Neuropsychiatry and Clinical Neurosciences·Beng-Yeong NgW L Lee
Jan 25, 2005·Emerging Infectious Diseases·Vincent P HsuRobert F Breiman
Jun 28, 2005·Journal of Neuropathology and Experimental Neurology·Ellen GelpiHerbert Budka
Jul 7, 2005·Proceedings of the National Academy of Sciences of the United States of America·Matthew I BonaparteChristopher C Broder
Jul 19, 2005·Emerging Infectious Diseases·Jean-Marc ReynesJean-Louis Sarthou
Feb 21, 2006·Emerging Infectious Diseases·Supaporn WacharapluesadeeThiravat Hemachudha

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Citations

Oct 1, 2011·Pathology Research International·K T Wong, K C Ong
Feb 26, 2013·Viruses·Timothy W PharesCornelia C Bergmann
Aug 16, 2015·Brain Pathology·Kien Chai Ong, Kum Thong Wong
Apr 10, 2012·Current Opinion in Virology·Christopher C Broder
Oct 16, 2014·Reviews in Medical Virology·Karen BohmwaldAlexis M Kalergis
Jul 11, 2013·Antiviral Research·Christopher C BroderLin-Fa Wang
Nov 24, 2012·The Journal of Infectious Diseases·Aurélie PloquinAnna Salvetti
Nov 2, 2014·The Neurohospitalist·Felicia C Chow, Carol A Glaser
Apr 22, 2011·Nature Reviews. Immunology·Dorian B McGavern, Silvia S Kang
Apr 4, 2012·Viruses·Deborah L SteffenChristopher C Broder
Jun 7, 2017·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Melissa LeachJames Koninga

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