Abstract
Background: Hand, foot and mouth disease (HFMD) is a common contagious disease among children under 5 years, particularly in the Asia-Pacific-region. We report a localized outbreak of childhood HFMD for the first time from Bangladesh, diagnosed only based on clinical features due to lack in laboratory-diagnostic facilities. Methods: Following the World Health Organization's case-definition, we conducted a rapid-appraisal of HFMD among all of the 143 children attending Pabna Medical College and General Hospital with fever, mouth ulcers and extremity rash. Data were collected between September and November 2017 using a preset syndromic approach and stringent differential diagnostic-protocols. Results: The mean age of children was 2.9±2.3 years. There was a significant difference among the age and sex of children (P=0.98), first sibling being more belonging to middle-income families (62%). Younger children (<5 years) were more likely to suffer with moderate-to-high (38.5°C) fever (P<0.04), painful oral ulcers (P<0.03) and painful/itchy rash (P<0.01). Sex did not differ with other symptoms, but boys had less painful oral ulcers than girls (P<0.04). Fever (63%) and chicken-pox-like-rash (62%) was observed more in mid-October to mid-...Continue Reading
References
Jan 6, 2010·Indian Journal of Dermatology·Nilendu SarmaRajib Malakar
Oct 23, 2010·Lancet Neurology·Mong How OoiTom Solomon
Feb 25, 2011·PloS One·Yien Ling HiiNawi Ng
Mar 23, 2011·Pediatrics·Feng RuanBao-Ping Zhu
May 9, 2012·PloS One·Christina ConnellYuanan Lu
Jun 26, 2012·Indian Pediatrics·Bikash Ranjan KarShantanu Kumar Kar
Mar 19, 2013·Vaccine·Yicun CaiZhong Huang
May 2, 2013·Emerging Infectious Diseases·Jiratchaya PuenpaYong Poovorawan
May 25, 2013·PloS One·Yunxia LiuFuzhong Xue
Jul 11, 2013·Human Vaccines & Immunotherapeutics·Chih-Wei LinMing-Hsi Huang
Feb 4, 2014·The Lancet Infectious Diseases·Weijia XingHongjie Yu
Mar 25, 2014·Vaccine·Yicun CaiZhong Huang
Oct 30, 2014·Revista Do Instituto De Medicina Tropical De São Paulo·Tiegang LiMing Wang
Dec 5, 2014·Annals of Dermatology·Eun Jee KimSoyun Cho
Apr 19, 2015·Clinics in Dermatology·Daniel VentarolaNanette Silverberg
Jun 27, 2015·Expert Review of Anti-infective Therapy·Lianlian BianZhenglun Liang
Jan 26, 2016·PloS One·Jiaqiang LiaoJuying Zhang
Jul 14, 2016·Medical Microbiology and Immunology·S AswathyrajD Hober
Aug 18, 2016·PloS One·Pin WangEmily Y Y Chan
Sep 13, 2016·International Journal of Environmental Research and Public Health·Ping-Chin ChangKow-Tong Chen
Mar 18, 2017·Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi·J Hy ChanJ Rudge
Apr 18, 2017·JAAD Case Reports·Anthony R Andreoni, Andrea S Colton
Jan 2, 2018·Virusdisease·Hau Van PhamCuong Q Hoang
Jan 8, 2018·The Science of the Total Environment·Qiang ChengHong Su