Emerging non-invasive approaches for diagnosis and monitoring of portal hypertension

The Lancet. Gastroenterology & Hepatology
Xiaolong QiShiv Kumar Sarin

Abstract

Clinically significant portal hypertension is associated with an increased risk of developing gastro-oesophageal varices and hepatic decompensation. Hepatic venous pressure gradient measurement and oesophagogastroduodenoscopy are the gold-standard methods for assessing clinically significant portal hypertension (hepatic venous pressure gradient ≥10 mm Hg) and gastro-oesophageal varices, respectively. However, invasiveness, cost, and feasibility limit their widespread use, especially if repeated and serial evaluations are required to assess the efficacy of pharmacotherapy. Although new techniques for non-invasive portal pressure measurement have been pursued for many decades, only recently have new tools been assessed and validated for larger clinical application. This Review focuses on the recent advances in non-invasive approaches for the diagnosis and serial monitoring of portal hypertension and varices for clinical practice.

Associated Clinical Trials

Citations

Jun 7, 2019·Hepatology International·Shiv Kumar SarinUNKNOWN APASL ACLF Research Consortium (AARC) for APASL ACLF working Party.
Sep 7, 2019·European Journal of Gastroenterology & Hepatology·Changchun LiuXiaolong Qi
Feb 20, 2020·Journal of Magnetic Resonance Imaging : JMRI·Stefanie J HectorsBachir Taouli
Jul 19, 2019·United European Gastroenterology Journal·Bernhard ScheinerMatthias Pinter
Jul 21, 2020·Exploration of Medicine·Marvin RyouGyorgy Baffy
Feb 29, 2020·Journal of Digestive Diseases·UNKNOWN Chinese Society of Hepatology, Chinese Medical Association; Chinese Society of Gastroenterology, Chinese Medical Association
Jan 8, 2021·European Radiology·Stefanie J HectorsBachir Taouli
Feb 6, 2021·Hepatology International·Sonia SeliceanJordi Gracia-Sancho
Dec 11, 2020·Gastroenterology Research and Practice·Chuan LiuXiaolong Qi
Apr 12, 2021·Clinics in Liver Disease·Élise Vuille-LessardAnnalisa Berzigotti
Apr 16, 2021·Expert Opinion on Emerging Drugs·Jonathan Andrew FallowfieldAndrew Robertson
Apr 30, 2021·Japanese Journal of Radiology·Ahmed Abdel Khalek Abdel RazekTarek Elsayed Barakat
May 14, 2021·Hepatology International·Xiaolong QiDon C Rockey
Mar 25, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Yanna LiuXiaolong Qi
Jun 25, 2021·Journal of Hepatology·UNKNOWN European Association for the Study of the Liver. Electronic address: easloffice@easloffice.euUNKNOWN Panel members:
Aug 4, 2021·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Jitao WangXiaolong Qi
Nov 18, 2021·Journal of Medical Ultrasonics·Xiaoguo LiYifei Huang
Dec 3, 2021·Technology in Cancer Research & Treatment·Wang XiaoqianZheng Peng

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