Emerging technologies for diagnostics and drug delivery in the fight against COVID-19 and other pandemics

Expert Review of Medical Devices
Dimitrios A Lamprou

Abstract

A pandemic is the worst-case scenario in the field of infectious diseases. Innovative technologies have the potential to address the challenges associated with the manufacture of personalized drug delivery systems, biosensors, and medical devices during a pandemic. 3D-Printing, microfluidics, and Microelectromechanical systems (MEMS) can provide an important part on this fight, as are cheap, easy to be operated, capable to provide rapid detection and monitoring of a disease, and deliver medicines. This manuscript answers the question of how these emerging technologies can save lives during a pandemic by avoiding supply chain delays and also by providing rapid diagnostics, disease monitoring, or by offering personalized treatments. The manuscript covers recent approaches in the topic with a focus in manuscripts published in the last year and by emphasising recent regulatory considerations by regulatory agencies in the manufacturing of 3DP systems or other medical devices during COVID. New manufacturing techniques are emerging with the ability to address the challenges associated with the development of medical devices or diagnostics, during a pandemic. Are many challenges in order to achieve this and especially in short times th...Continue Reading

References

Nov 9, 2017·Advanced Drug Delivery Reviews·Hyunjoo J LeeIl-Joo Cho
Mar 15, 2018·Lab on a Chip·Michael A LuzuriagaJeremiah J Gassensmith
May 31, 2019·Materials Science & Engineering. C, Materials for Biological Applications·Sophia N EconomidouDennis Douroumis
Jul 5, 2019·Nature Nanotechnology·Hon S LeongChiara Pastore
Nov 7, 2019·Expert Opinion on Drug Delivery·Dimitrios A LamprouRyan F Donnelly
Feb 23, 2020·Scientific Reports·Yi-Kuang Yen, Chao-Yuan Chiu
Mar 3, 2020·Journal of Autoimmunity·Hussin A Rothan, Siddappa N Byrareddy
Mar 19, 2020·Pharmaceutics·Essyrose MathewDimitrios A Lamprou
Mar 24, 2020·Nature Biotechnology·Cormac Sheridan
Apr 1, 2020·ACS Nano·Buddhisha UdugamaWarren C W Chan
Apr 22, 2020·Expert Review of Medical Devices·Jorge M Zuniga, Aaron Cortes
Apr 30, 2020·Nature·Ewen Callaway

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Citations

Sep 15, 2020·Molecular Diagnosis & Therapy·Thomas UsherwoodAnubhav Tripathi
Oct 16, 2020·Nature Reviews. Microbiology·Olivier VandenbergZisis Kozlakidis
Jan 29, 2021·International Journal of Environmental Research and Public Health·Yoonje Euh, Daeho Lee
Apr 8, 2021·ACS Sensors·Giorgia GiovanniniDenis Garoli
May 9, 2021·Journal of Medical Virology·Matthew M HernandezAlberto E Paniz-Mondolfi

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