Emerging tobacco-related cancer risks in China: A nationwide, prospective study of 0.5 million adults

Cancer
Zheng-Ming ChenChina Kadoorie Biobank Collaborative Group

Abstract

In China, cigarette consumption has increased substantially since the 1980s, almost exclusively in men. This study was aimed at assessing the emerging cancer risks. A nationwide, prospective study recruited 210,259 men and 302,632 women aged 30 to 79 years from 10 areas of China from 2004 to 2008; approximately 18,000 incident cancers were recorded during 7 years of follow-up. Cox regression yielded adjusted risk ratios (RRs) comparing smokers (including those who had stopped because of illness but not those who had stopped by choice) with never-smokers. Among men, 68% were smokers; their overall cancer risk was significantly increased (RR, 1.44; 95% confidence interval [CI], 1.37-1.53), and it was greater in urban (RR, 1.55; 95% CI, 1.41-1.70) than in rural areas (RR, 1.39; 95% CI, 1.30-1.49). This excess accounted for 23% of all cancers between the ages of 40 and 79 years, with significantly elevated risks of lung cancer (RR, 2.51; 95% CI, 2.18-2.90), liver cancer (RR, 1.32; 95% CI, 1.12-1.54), stomach cancer (RR, 1.34; 95% CI, 1.16-1.55), esophageal cancer (RR, 1.47; 95% CI, 1.24-1.73), and an aggregate of 5 other minor sites (RR, 1.52; 95% CI, 1.25-1.86). For lung cancer, the RRs were much greater for nonadenocarcinoma (RR,...Continue Reading

References

Jun 5, 1996·JAMA : the Journal of the American Medical Association·J M YuanM C Yu
Nov 18, 1997·JAMA : the Journal of the American Medical Association·T H LamB Q Liang
May 16, 1998·American Journal of Public Health·B RockhillC Weinberg
Nov 20, 1998·BMJ : British Medical Journal·S R NiuR Peto
Jan 12, 1999·Nature Medicine·R PetoJ Boreham
Oct 12, 1999·JAMA : the Journal of the American Medical Association·G YangJ Xu
Jun 24, 2004·BMJ : British Medical Journal·Richard DollIsabelle Sutherland
Sep 1, 2005·International Journal of Epidemiology·Zhengming ChenRichard Peto
Sep 8, 2005·International Journal of Epidemiology·Gonghuan YangAlan D Lopez
Jan 9, 2009·The New England Journal of Medicine·Dongfeng GuJiang He
May 1, 2009·The New England Journal of Medicine·Ruoling Chen
Mar 11, 2010·Cancer Causes & Control : CCC·Jian-Bing WangPaolo Boffetta
Dec 14, 2011·International Journal of Epidemiology·Zhengming ChenUNKNOWN China Kadoorie Biobank (CKB) collaborative group
Jun 13, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J B WangP Boffetta
Oct 31, 2012·Lancet·Kirstin PirieUNKNOWN Million Women Study Collaborators
Jan 25, 2013·The New England Journal of Medicine·Prabhat JhaRichard Peto
Jan 25, 2013·The New England Journal of Medicine·Michael J ThunSusan M Gapstur
Sep 24, 2013·International Journal of Epidemiology·Qiuli ZhangUNKNOWN China Kadoorie Biobank study collaboration
Sep 7, 2014·The Lancet. Respiratory Medicine·Stephen B GordonWilliam J Martin
Nov 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J B WangP Boffetta

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Citations

Jan 26, 2016·CA: a Cancer Journal for Clinicians·Wanqing ChenJie He
Sep 4, 2015·Cancer·Electra D PaskettFadlo R Khuri
Mar 26, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Anne S TsaoHarvey I Pass
Aug 16, 2016·International Journal of Cancer. Journal International Du Cancer·Miranda M FidlerFreddie Bray
Aug 9, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Emily C A StoneUNKNOWN International Association for the Study of Lung Cancer Tobacco Control Committee
Sep 18, 2016·Tobacco Control·Deliana KostovaFrank J Chaloupka
May 23, 2019·International Journal of Cancer. Journal International Du Cancer·Lu WangUNKNOWN China Kadoorie Biobank Collaborative Group
May 10, 2019·NPJ Precision Oncology·Hongbing ShenCheng Wang
Jul 1, 2020·Annals of the American Thoracic Society·Marissa ReitsmaVin Gupta
Nov 5, 2016·Journal of Cancer Research and Clinical Oncology·Antonio Carlos de FreitasCarolina Maria Medeiros do Amaral
Jan 27, 2017·Oncology Letters·Jing HuangYue Hu
Jul 10, 2018·International Journal of Epidemiology·Maarit A LaaksonenClaire M Vajdic
Oct 28, 2019·International Journal of Epidemiology·Ka Hung ChanUNKNOWN China Kadoorie Biobank Study Group
Oct 2, 2020·International Journal of Environmental Research and Public Health·Qike JiaQichuan Tang
Aug 9, 2020·Contrast Media & Molecular Imaging·Long ZhaoHuoqiang Wang
May 4, 2017·World Journal of Gastroenterology : WJG·Dao-Juan LiYu-Tong He
Jun 9, 2017·International Journal of Cancer. Journal International Du Cancer·Rui PanUNKNOWN China Kadoorie Biobank Collaborative Group
Jun 18, 2020·Tobacco Induced Diseases·Linjie YuJianbing Wang
Dec 15, 2020·The Science of the Total Environment·Huagui GuoWeifeng Li
Mar 5, 2021·Cancer Communications·Ning LiJingmei Jiang
Feb 27, 2021·International Journal of Cancer. Journal International Du Cancer·Pek Kei ImUNKNOWN China Kadoorie Biobank (CKB) Collaborative Group
May 1, 2021·Journal of Gastroenterology and Hepatology·Yongjia LiuXingxiang He
Sep 30, 2017·Annals of Oncology : Official Journal of the European Society for Medical Oncology·F IslamiA Jemal
Nov 25, 2021·Environmental Science and Pollution Research International·Huagui GuoHung Chak Ho

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