Emmetropization and eye growth in young aphakic chickens.

Investigative Ophthalmology & Visual Science
Likun AiChristine F Wildsoet

Abstract

To establish a chick model to investigate the trends of eye growth and emmetropization after early lensectomy for congenital cataract. Four monocular treatments were applied: lens extraction (LX); sham surgery/-30 D lens; LX/+20 D lens; and LX/+30-D lens (nine per group). Lens powers were selected to slightly undercorrect or overcorrect the induced hyperopia in LX eyes and to induce comparable hyperopia in sham-surgery eyes. Refractive errors and axial ocular dimensions were measured over a 28-day period. External ocular dimensions were obtained when the eyes were enucleated on the last day. The growth patterns of experimental (Exp) eyes varied with the type of manipulation. All eyes experiencing hyperopia initially grew more than their fellow eyes and exhibited myopic shifts in refraction. The sham/-30 D lens group showed the greatest increase in optical axial length, followed by the LX group, and then the LX/+20 D lens group. The Exp eyes of the LX/+30 D lens group, which were initially slightly myopic, grew least, and showed a small hyperopic shift. Lensectomized eyes enlarged more equatorially than axially (i.e., oblate), irrespective of the optical treatment applied. The refractive changes observed in young, aphakic eyes a...Continue Reading

References

Sep 1, 1979·Ophthalmology·A J Coulombre
Jan 1, 1988·Vision Research·F SchaeffelH C Howland
Jan 1, 1986·Vision Research·G W van Alphen
May 1, 1995·Vision Research·L Kiorpes, J Wallman
Jun 1, 1994·Vision Research·A GlasserH C Howland
Jul 1, 1997·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·C F Wildsoet
Apr 17, 1998·Current Eye Research·S T NevinC F Wildsoet
Jul 14, 1998·Optometry and Vision Science : Official Publication of the American Academy of Optometry·E L Smith
Jun 12, 1999·The British Journal of Ophthalmology·D I FlitcroftM O'Keefe
Jul 23, 1999·Optometry and Vision Science : Official Publication of the American Academy of Optometry·E L SmithR G Boothe
Sep 7, 1999·Journal of Cataract and Refractive Surgery·E D GrienerS R Lambert
Jan 1, 2000·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·E L SmithR S Harwerth
Mar 10, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·J A BeresfordD P Crewther
Aug 17, 2001·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·M E WilsonL A Elliott
Jan 22, 2003·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Katrina L SchmidChristine F Wildsoet
Jun 1, 1964·The Journal of Experimental Zoology·A J COULOMBRE, J L COULOMBRE
Dec 24, 2004·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Paul W HardwigHelmut Buettner
Jan 5, 2005·American Journal of Ophthalmology·Abhay R VasavadaBharti Nihalani
Aug 17, 2005·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Garima LalM Millicent Peterseim
Jan 27, 2006·Current Opinion in Ophthalmology·Adrian Glasser
Feb 24, 2006·American Journal of Ophthalmology·Shimon RumeltUri Rehany
Feb 3, 2007·Ophthalmology·Maya Eibschitz-TsimhoniMonte A Del Monte

❮ Previous
Next ❯

Citations

May 26, 2005·Vision Research·Michael J CollinsD Robert Iskander
Dec 10, 2009·Current Opinion in Ophthalmology

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Shinsuke MiyaharaHidenobu Tanihara
© 2022 Meta ULC. All rights reserved