Emotion recognition during cocaine intoxication

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology
K P C KuypersJ G Ramaekers

Abstract

Chronic or repeated cocaine use has been linked to impairments in social skills. It is not clear whether cocaine is responsible for this impairment or whether other factors, like polydrug use, distort the observed relation. We aimed to investigate this relation by means of a placebo-controlled experimental study. Additionally, associations between stressor-related activity (cortisol, cardiovascular parameters) induced by the biological stressor cocaine, and potential cocaine effects on emotion recognition were studied. Twenty-four healthy recreational cocaine users participated in this placebo-controlled within-subject study. Participants were tested between 1 and 2 h after treatment with oral cocaine (300 mg) or placebo. Emotion recognition of low and high intensity expressions of basic emotions (fear, anger, disgust, sadness, and happiness) was tested. Findings show that cocaine impaired recognition of negative emotions; this was mediated by the intensity of the presented emotions. When high intensity expressions of Anger and Disgust were shown, performance under influence of cocaine 'normalized' to placebo-like levels while it made identification of Sadness more difficult. The normalization of performance was most notable fo...Continue Reading

References

Aug 1, 1995·The American Journal of the Medical Sciences·C M HeeschE J Eichhorn
Apr 1, 1996·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·E SeifritzE Holsboer-Trachsler
Oct 23, 1997·Neuron·H C BreiterS E Hyman
Nov 15, 2002·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Harriet de WitJerry B Richards
Mar 4, 2003·Nature Reviews. Neuroscience·Ralph Adolphs
Mar 18, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Simon Baron-CohenSally Wheelwright
Apr 10, 2004·Journal of Cognitive Neuroscience·Ralph Adolphs, Daniel Tranel
May 5, 2004·Psychological Bulletin·Sally S Dickerson, Margaret E Kemeny
Jun 17, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Nancy K MelloMegan E Roth
Mar 17, 2007·Journal of Affective Disorders·Wendelien MerensPhilip Spinhoven
Jun 8, 2007·Psychopharmacology·L KemmisM J Morgan
May 23, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Patricia A WoicikRita Z Goldstein
Mar 26, 2009·Behavioral Sciences & the Law·Elizabeth A ShirtcliffCarolyn Zahn-Waxler
May 21, 2009·Nature Reviews. Neuroscience·Amy F T Arnsten
Jul 15, 2009·Biological Psychiatry·Hein J F van MarleGuillén Fernández
Jan 13, 2010·Drug and Alcohol Dependence·María José Fernández-SerranoAntonio Verdejo-García
Feb 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Jack van HonkSimon Baron-Cohen
Apr 25, 2012·Psychopharmacology·Margaret C WardleHarriet de Wit
Jun 27, 2013·Addiction Biology·Katrin H PrellerBoris B Quednow
Jul 24, 2013·Neuroscience and Biobehavioral Reviews·Desirée B SpronkRobbert J Verkes
Oct 10, 2013·The International Journal of Neuropsychopharmacology·Cédric M HysekMatthias E Liechti
Dec 7, 2013·Psychopharmacology·Petra J J BaarendseLouk J M J Vanderschuren
Jan 23, 2014·Proceedings of the National Academy of Sciences of the United States of America·Katrin H PrellerBoris B Quednow
Apr 14, 2015·Psychological Medicine·L P CapitãoC J Harmer

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Citations

Oct 18, 2018·Addiction Biology·Gillinder BediMargaret Haney
Jul 24, 2020·Social Cognitive and Affective Neuroscience·Navot NaorHadas Okon-Singer
Feb 18, 2020·Frontiers in Pharmacology·Esther PapaseitMagí Farré
Sep 9, 2020·Drug and Alcohol Dependence·Amy R Bland, Karen D Ersche

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