Abstract
Latent autoimmune diabetes in adults (LADA) refers to an autoimmune disorder characterized with detectable islets antibodies in the early diagnosis and increased autoimmune beta-cell failure progression. Notably, this kind of diabetes seems to be confused with other phenotypic diabetes. A young woman suffered an emotional exhaustion-induced LADA, showing asthenia, polydipsia, polyuria, and visible weight loss. The patient emotionally ended a 14-year romantic relationship, leading to the emotional flooding. The data from physical examination and laboratory tests exhibited as follows: glutamic acid decarboxylase antibody (GADA) = 63.83 U/mL, the fasting blood glucose (FBG) = 13.3 mmol/L, and glycated haemoglobin (HbA1c) = 10.9%. According to levels of GADA, the patient was diagnosed as LADA. The patient was clinically treated with insulin for 3-month. Then, running, diet-control, and emotional treatment were combined, such as the patient started a new relationship. An emotional recovery initiated from a new romantic relationship and a baby, showing normal levels of GAD65 (27.007 IU/mL) and FBG (5.46) mmol/L. The emotional exhaustion might play a significant role in induction of LADA. It is important that individuals should mainta...Continue Reading
References
Mar 11, 1976·The Journal of Clinical Investigation·R P RobertsonD Porte
Feb 1, 1989·Endocrine Reviews·A BatemanS Solomon
Jan 1, 1988·Diabetes Care·R S Surwit, M N Feinglos
Feb 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·J K Wales
Jan 22, 2002·Journal of Psychosomatic Research·Paul H Black, Lisa D Garbutt
Aug 30, 2003·Brain, Behavior, and Immunity·Paul H Black
Jan 16, 2014·Autoimmunity Reviews·Silvia Canivell, Ramon Gomis
Jul 19, 2016·Primary Care Diabetes·Andreas Liebl
Oct 30, 2016·Immunology Letters·Bangqing YuanZhao Yang
Oct 30, 2016·Immunology Letters·Lamia Ysmail-DahloukMourad Aribi
Nov 5, 2016·Immunology Letters·Anne KresinskyJörg P Müller
Nov 5, 2016·Immunology Letters·Min ZhangShufa Li
Nov 5, 2016·Immunology Letters·Marcelo Arantes LevenhagenJulia Maria Costa-Cruz
Nov 7, 2016·Immunology Letters·Tujing GuoHuangjin Li
Nov 7, 2016·Immunology Letters·Loredana CifaldiCristina Cerboni
Nov 9, 2016·Immunology Letters·Cristina CapittiniCarmine Tinelli
Nov 12, 2016·Immunology Letters·Min ZhangShufa Li
Nov 12, 2016·Immunology Letters·Bing YanShun Chen
Nov 14, 2016·Immunology Letters·Andreia RibeiroRhodri Ceredig
Nov 14, 2016·Immunology Letters·Tomonori NagayaShingo Ichimiya
Nov 14, 2016·Immunology Letters·Raffaella Mormile
Nov 14, 2016·Immunology Letters·Enza D'AuriaGiorgio Ciprandi
Nov 14, 2016·Immunology Letters·Naglaa Abd Elrahman MosaadRasha Mohamad Hosny Shahin
Nov 15, 2016·Immunology Letters·Ferjani ZouidiH Masmoudi
Nov 16, 2016·Immunology Letters·Allan V RodriguesShamkant B Badgujar
Dec 8, 2016·Immunology Letters·Hongye FanYayi Hou
Dec 13, 2016·Immunology Letters·Nasser GholijaniEskandar Kamali-Sarvestani
Dec 17, 2016·Immunology Letters·Leila RahbarniaMohammad Kazem Hosseini
Dec 17, 2016·Immunology Letters·Donato Rigante, Raffaele Manna