En bloc resection for primary and metastatic tumors of the spine: a systematic review of the literature

Neurosurgery
Jordan M CloydChristopher P Ames

Abstract

The efficacy of en bloc resection for spinal tumors is unknown because most of the current evidence is provided by small, single-institution clinical series or case reports. To combine all previously published reports of en bloc resection for primary and metastatic spinal tumors, to describe the overall pattern of disease-free survival, and to investigate potentially prognostic factors for recurrence. A complete MEDLINE search for all articles reporting survival data for en bloc resection of spinal tumors was undertaken; 44 articles met inclusion criteria from which 306 eligible patients were identified. There were 229 cases of primary tumors with a mean follow-up of 65.0 months and 77 cases of solitary metastatic tumors with a mean follow-up of 26.5 months. Median time to recurrence was 113 months for the primary group and 24 months for the metastatic group. Disease-free survival rates at 1, 5, and 10 years were 92.6%, 63.2%, and 43.9%, respectively, for the primary group and 61.8%, 37.5%, and 0%, respectively, for the metastatic group; 5-year disease-free survival rates were 58.4% for chordoma and 62.9% for chondrosarcoma. After adjusting for covariates, age, male sex, metastatic tumors, and osteosarcomas were significantly a...Continue Reading

References

Nov 1, 1990·Spine·K Tomita, H Tsuchiya
Oct 1, 1989·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·N SundaresanJ E Hughes
Nov 1, 1987·Spine·J N Weinstein, R F McLain
Oct 1, 1994·International Orthopaedics·K TomitaY Toribatake
Nov 1, 1993·The Journal of Bone and Joint Surgery. American Volume·S GitelisF Turner
Sep 1, 1996·Journal of Neurosurgery·N SundaresanK Kelliher
Oct 1, 1996·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·C CattonJ Wunder
Dec 31, 1998·Surgical Neurology·R F HearyJ M Cotler
Jan 23, 1999·Neurosurgery·J E YorkZ L Gokaslan
Jul 21, 1999·Journal of Neurosurgery·J E YorkZ L Gokaslan
Apr 6, 2000·Spine·S BorianiP Bacchini
Sep 23, 2000·Surgical Endoscopy·M van DijkP I Wuisman
Feb 27, 2001·Spine·K TomitaT Akamaru
Apr 17, 2001·Journal of Neurosurgery·J J BosmaD C Jaffray
Jan 24, 2002·Spine·Jun NishidaTadashi Shimamura
Feb 15, 2002·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·M el-S Abdel-WanisK Tomita
Apr 16, 2002·Clinical Orthopaedics and Related Research·Robert TalacFranklin H Sim
Jul 18, 2002·Journal of Neurosurgery·Ken IshiiYoshiaki Toyama
Aug 22, 2002·The Journal of Bone and Joint Surgery. British Volume·P KreplerR Kotz
Apr 23, 2003·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Georges NoëlJean-Jacques Mazeron
Jun 18, 2003·Spine·Maurits van TulderUNKNOWN Editorial Board of the Cochrane Collaboration Back Review Group
Aug 5, 2003·Spine·Minoru DoitaMasahiro Kurosaka
Sep 23, 2003·Spine·Denis S Drummond
Sep 23, 2003·Spine·Roberto BiaginiMario Mercuri
Nov 13, 2003·Clinical Orthopaedics and Related Research·William F EnnekingMark A Goodman
Jul 29, 2004·Journal of Spinal Disorders & Techniques·Hironobu SakauraHideki Yoshikawa
Sep 17, 2004·Cancer·Paolo G CasaliSilvana Pilotti
Apr 2, 2005·Spine·Rex A W MarcoZiya L Gokaslan
Sep 1, 2005·Clinical Orthopaedics and Related Research·Ian D DickeyFranklin H Sim
Nov 4, 2005·Journal of Neurosurgery. Spine·Peter C GersztenDavid M Friedland
Dec 24, 2005·Journal of Neurosurgery. Spine·Daryl R FourneyZiya L Gokaslan
Jan 27, 2006·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Katsuro TomitaSatoru Demura

❮ Previous
Next ❯

Citations

Aug 31, 2013·Der Orthopäde·C DruschelK-D Schaser
Apr 12, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Praveenan SivabalanRalph J Mobbs
Aug 7, 2012·Journal of Neurosurgery. Spine·Ganeshwaran ShivapathasundramBalsam Darwish
Oct 24, 2013·Annals of Surgical Oncology·Satoshi KatoHiroyuki Tsuchiya
Jan 29, 2016·Current Treatment Options in Oncology·Raphaële Charest-MorinCharles G Fisher
Mar 3, 2015·Neurosurgical Focus·James P CarusoJason P Sheehan
Feb 9, 2016·Spine·Charles G FisherLaurence D Rhines
Aug 2, 2016·Neurosurgical Focus·Viren S VasudevaMichael W Groff
Sep 10, 2015·Arquivos de neuro-psiquiatria·Andrei F JoaquimMark H Bilsky
Feb 12, 2017·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S StacchiottiJ Sommer
Jun 19, 2013·Surgical Neurology International·Salvatore Di MaioRobert Rostomily
Sep 15, 2018·Medicine·Takaki ShimizuHiroyuki Tsuchiya
Mar 17, 2018·Neurologia i neurochirurgia polska·Kyriakos ParaskevaMarios S Themistocleous
Feb 17, 2019·Journal of Neurosurgery. Spine·Garrett K BergerR John Hurlbert
May 11, 2019·Brain Sciences·Christopher HeinrichTanya Minasian
Sep 29, 2019·Journal of Neurosurgery. Spine·Raphaële Charest-MorinNicolas Dea
Sep 6, 2017·The Journal of Bone and Joint Surgery. American Volume·Akash A ShahJoseph H Schwab
Feb 27, 2018·Neurosurgery·Ori BarzilaiMark H Bilsky
Jul 21, 2011·Neurosurgery·Hormuzdiyar H DasenbrockJean-Paul Wolinsky
Mar 29, 2014·Cancer Control : Journal of the Moffitt Cancer Center·Paul E KaloostianDaniel M Sciubba
Nov 30, 2013·The Journal of Bone and Joint Surgery. American Volume·Robert H QuinnKevin A Raskin
Dec 20, 2017·Spine Surgery and Related Research·Katsuhito YoshiokaHiroyuki Tsuchiya
Jul 30, 2020·F1000Research·Scott W ConnorsCarlos A Bagley
Nov 18, 2020·Journal of Orthopaedic Surgery and Research·Hongyu WeiHaoning Ma
Feb 24, 2021·Journal of Korean Medical Science·Jong Myung JungKi Jeong Kim
Sep 2, 2020·Clinical Spine Surgery : a Spine Publication·David C KieserJeremy Reynolds

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.