En bloc spondylectomy for treatment of tumor-induced osteomalacia

Journal of Neurosurgery. Spine
Daniel M SciubbaJean-Paul Wolinsky

Abstract

En bloc spondylectomy represents a radical resection of a spinal segment most often reserved for patients presenting with a primary extradural spine tumor or a solitary metastasis in the setting of an indolent, well-controlled systemic malignancy. The authors report a case in which en bloc spondylectomy was conducted to control a metabolically active spine tumor. A 56-year-old woman, who suffered from severe tumor-induced osteomalacia, was found to have a fibroblast growth factor-23-secreting phosphaturic mesenchymal tumor in the T-8 vertebral body. En bloc resection was conducted, leading to resolution of her tumor-induced osteomalacia. This case suggests that radical spondylectomy may be beneficial in the management of metabolically or endocrinologically active tumors of the spine.

References

Dec 1, 1986·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·N SundaresanI S Choi
Aug 1, 1995·Seminars in Arthritis and Rheumatism·D SchapiraL A Best
Oct 7, 1998·Journal of Neurosurgery·Z L GokaslanR Sawaya
Jan 23, 1999·Neurosurgery·J E YorkZ L Gokaslan
Jul 21, 1999·Journal of Neurosurgery·J E YorkZ L Gokaslan
Jun 11, 2002·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Suzanne M Jan De BeurSusan C Schiavi
Jan 22, 2004·Biochemical and Biophysical Research Communications·Takashi ShimadaTakeyoshi Yamashita
Mar 26, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Takashi ShimadaTakeyoshi Yamashita
May 29, 2004·Current Opinion in Otolaryngology & Head and Neck Surgery·Stuart D Thompson, Andrew J N Prichard
Aug 5, 2005·The New England Journal of Medicine·Tali CukiermanTova Chajek-Shaul
Dec 17, 2005·Current Opinion in Oncology·Steven E Rodgers, Nancy D Perrier
Dec 17, 2005·Current Opinion in Oncology·Theresia WeberMarkus W Büchler
Dec 22, 2005·The Laryngoscope·Christian T UlrichSalvatore C Lettieri
Dec 23, 2006·Surgical Oncology·Daniel M Sciubba, Ziya L Gokaslan
Dec 25, 2007·Neurosurgery Clinics of North America·Daniel M SciubbaZiya L Gokaslan
Jan 25, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ulf LiljenqvistWinfried Winkelmann
Mar 21, 2008·The New England Journal of Medicine·Jill E Vollbrecht, D Sudhaker Rao
Oct 1, 2005·Nanotechnology·Lu ZhangCheng Wang

❮ Previous
Next ❯

Citations

Oct 23, 2013·Annals of Surgical Oncology·P E KaloostianZ L Gokaslan
Apr 15, 2011·Endocrine-related Cancer·William H ChongMichael T Collins
Feb 1, 2011·Journal of Neurosurgery. Spine·Murtaza AkhterYevgeniy A Khavkin
Apr 27, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Peter J PuthenveetilEric M Horn
Oct 18, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·C Rory GoodwinDaniel M Sciubba
Feb 8, 2014·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Takeshi NakamuraShoichi Kokubun
May 26, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Panagiota AndreopoulouMichael T Collins
Apr 22, 2016·Global Spine Journal·C Rory GoodwinDaniel M Sciubba
Jul 3, 2015·The Journal of Bone and Joint Surgery. American Volume·Hai WangJin Jin
Jul 2, 2019·Advances in Anatomic Pathology·Michele BiscegliaAlfredo Scillitani
Mar 29, 2014·Cancer Control : Journal of the Moffitt Cancer Center·Paul E KaloostianDaniel M Sciubba
Nov 7, 2017·Case Reports in Rheumatology·Sara BeygiTarun S Sharma
Jul 14, 2017·Nature Reviews. Disease Primers·Salvatore MinisolaMichael T Collins

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Seminars in Musculoskeletal Radiology
Kelli Andresen Edmister, Murali Sundaram
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Suzanne M Jan De BeurSusan C Schiavi
© 2022 Meta ULC. All rights reserved