Abstract
Recent data have shown that en bloc infant kidneys transplanted to adult recipients functioned well. Longterm graft survival and function are not available, however. This study analyzes the 10-year experience with transplantation of en bloc infant kidneys from 1987-1997. This is a chart review of adult recipients of en bloc infant kidneys with respect to donors' and recipients' age, weight, creatinine, HLA antigen matching, panel reactive antibodies, cold ischemia time, surgical complications, original disease, and longterm graft function and survival. Five en bloc kidneys thrombosed (6.4%). Two ureteral fistulas were repaired successfully. Five patients underwent dialysis (6.4%). Two patients died of infection, six of heart attack and stroke, and one of cancer. All had excellent graft function at patients' death. Renal artery stenosis was dilated in seven patients. Six grafts were lost to rejection (one from noncompliance at 20 months). The original disease recurred in three patients with massive proteinuria despite excellent function. Graft survival at 43 months (range, 6-123 months) was 79%, with serum creatinine levels at 1, 3, 9 and 10 years of 1.2, 1.0, 0.8 and 0.8 mg/dl, respectively. Creatinine clearance averaged 88 mL/...Continue Reading
References
Aug 1, 1992·Journal of the American Society of Nephrology : JASN·B M BrennerE L Milford
Jan 1, 1991·The Journal of Urology·D D Nghiem
Jan 1, 1988·Transplantation·J M HayesD R Steinmuller
Jan 1, 1988·Transplantation·R H KermanB D Kahan
Dec 1, 1974·Journal of Clinical Ultrasound : JCU·R J BartrumJ Dantono
Sep 1, 1972·Transplantation·F O BelzerS L Kountz
Jan 1, 1974·Archives of Surgery·O S AndersenF K Merkel
Mar 1, 1974·American Journal of Surgery·D W KinneJ S Najarian
Sep 1, 1983·Clinical Nuclear Medicine·G F Gates
Apr 1, 1983·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·T B JonesD Samuels
Feb 1, 1995·The Journal of Urology·D D NghiemJ D Schlosser
Nov 15, 1996·Transplantation·R ShapiroT E Starzl
Jan 27, 1997·Transplantation·P N BretanF Vincenti
May 27, 1997·Transplantation·R SatterthwaiteR Mendez
Jan 1, 1908·The Journal of Experimental Medicine·A Carrel
Citations
Mar 27, 2001·Transplantation Proceedings·G Varela-FascinettoJ Nieto
Jun 28, 2003·Transplantation·Dai D Nghiem
Jun 16, 2010·Transplantation·Suverta BhayanaKanae Ishihara
May 13, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Vikas R DharnidharkaRichard J Howard
May 10, 2005·Clinical Transplantation·Rafik El-Sabrout, Kerri Buch
Mar 1, 2012·Pediatric Transplantation·Vidyadhar MaliPrabhakaran Krishnan
Oct 31, 2001·Transplantation·D D Nghiem
Mar 25, 2016·World Journal of Transplantation·Yousef Al-ShraidehRobert J Stratta
Sep 20, 2002·Journal of the American Society of Nephrology : JASN·Emilio RamosWilliam E Harmon