PMID: 8583592Mar 1, 1996Paper

En bloc transplantation of kidneys from pediatric donors

The Journal of Urology
A J Amante, B D Kahan

Abstract

Cadaveric kidneys from pediatric donors represent an important resource for human allotransplantation. We report 7 cases in which a new technique was used for en bloc transplantation of pediatric cadaver kidneys into adult recipients. Paired cadaveric kidneys obtained from donors younger than 6 years (mean age 26 months) were transplanted en bloc into 2 children (mean age 12.5 years) and 5 adults (mean age 50 years) using en bloc extraperitoneal interposition of the donor aorta and vena cava into the recipient external iliac artery and vein. All patients had excellent perfusion immediately following transplantation on 99mtechnetium-pentetic acid perfusion scans. Serum creatinine decreased to its nadir an average of 7 days post-transplantation in all but 1 patient. In 3 patients glomerular filtration rate increased 3 to 5-fold at 3 months and 6 months after transplantation. No patient had venous or arterial thrombosis postoperatively and 2 had ureteral leaks. In 3 patients moderate to severe biopsy proved acute rejection episodes were successfully reversed by intensifying immunosuppressive treatment and recovery episodes were successfully reversed by intensifying immunosuppressive treatment and recovery of allograft function was...Continue Reading

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Citations

Nov 13, 2003·Transplantation Proceedings·K A BeasleyP P W Luke
Apr 13, 1999·The American Journal of Surgical Pathology·T NadasdyL Racusen
Mar 10, 2001·Transplantation·A I Sánchez-FructuosoA Barrientos
Jan 16, 2007·Transplantation·Liise K KaylerErnesto Molmenti
Jun 16, 2010·Transplantation·Suverta BhayanaKanae Ishihara
Apr 12, 2017·Pediatric Transplantation·H C YaffeL K Kayler
Feb 16, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Helong DaiShaojie Yu

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