En face OCT angiography demonstrates flow in early type 3 neovascularization (retinal angiomatous proliferation)

Eye
K K DansinganiK Bailey Freund

Abstract

The characteristics of type 3 neovascularization (NV), also known as retinal angiomatous proliferation, have been well described clinically, as well as with fluorescein angiography (FA), indocyanine green angiography, and optical coherence tomography (OCT). OCT angiography (OCT-A) is a novel and non-invasive technique for imaging retinal microvasculature by detecting changes, with respect to time, in reflectivity related to blood flow. In this case series, we describe two patients who presented with type 3 NV and underwent clinical examination and multimodal imaging, including OCT-A. In the first patient, OCT-A demonstrated flow within two separate lesions in the same eye, one of which was only weakly detected by FA. In the second patient, sequential OCT-A demonstrated a reduction in intralesional flow following intravitreal therapy. OCT-A may have a role in the early diagnosis of type 3 NV and in assessing the response to treatment. Further studies are needed to determine sensitivity and specificity.

References

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Citations

Dec 24, 2015·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·P P FangF G Holz
Aug 27, 2015·Progress in Retinal and Eye Research·Ursula Schmidt-Erfurth, Sebastian M Waldstein
Dec 1, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ju Young KimYong Sung You
Oct 28, 2015·BioMed Research International·Alex D PechauerYali Jia
May 18, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Gena DamentoTheodore Leng
Jun 29, 2016·American Journal of Ophthalmology·Kunal K DansinganiK Bailey Freund
Oct 16, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·J MaaßE Matthé
Apr 7, 2018·European Journal of Ophthalmology·Marco LupidiCarlo Cagini
Jan 30, 2016·World Journal of Surgery·Rachel A HadlerAdam L Kushner
Sep 29, 2015·Retina·Chandrakumar BalaratnasingamK Bailey Freund
Nov 16, 2019·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·D VallerM Maier
May 28, 2016·Biomedical Optics Express·Miao ZhangYali Jia
Aug 7, 2015·International Journal of Retina and Vitreous·Orly Gal-OrK Bailey Freund
Oct 6, 2017·Vestnik oftalmologii·M V BudzinskayaP A Sorokin
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Mar 27, 2020·Ophthalmic Surgery, Lasers & Imaging Retina·Jianbo MaoLijun Shen
Dec 13, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ankur SinghVishali Gupta
Sep 2, 2020·Klinische Monatsblätter für Augenheilkunde·Felix HeineGabriele E Lang
Nov 27, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tommaso BacciK Bailey Freund
Mar 27, 2021·Progress in Retinal and Eye Research·Tristan T HormelYali Jia
Apr 22, 2021·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Maged AlnawaisehNicole Eter

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