Enantiomer-Selective Molecular Sensing Using Racemic Nanoplasmonic Arrays

Nano Letters
Jose García-GuiradoRomain Quidant

Abstract

Building blocks of life show well-defined chiral symmetry which has a direct influence on their properties and role in Nature. Chiral molecules are typically characterized by optical techniques such as circular dichroism (CD) where they exhibit signatures in the ultraviolet frequency region. Plasmonic nanostructures have the potential to enhance the sensitivity of chiral detection and translate the molecular chirality to the visible spectral range. Despite recent progress, to date, it remains unclear which properties plasmonic sensors should exhibit to maximize this effect and apply it to reliable enantiomer discrimination. Here, we bring further insight into this complex problem and present a chiral plasmonic sensor composed of a racemic mixture of gammadions with no intrinsic CD, but high optical chirality and electric field enhancements in the near-fields. Owing to its unique set of properties, this configuration enables us to directly differentiate phenylalanine enantiomers in the visible frequency range.

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Citations

Dec 10, 2019·Nanoscale·Yoon Young LeeKi Tae Nam
Mar 17, 2020·Chemical Society Reviews·Xueli ZhaoXiaoyuan Chen
May 18, 2019·Light, Science & Applications·Yang ChenJie Gao
Sep 15, 2020·Light, Science & Applications·Jungho MunJunsuk Rho
Feb 8, 2020·Physical Review Letters·Joshua FeisIvan Fernandez-Corbaton
Nov 7, 2019·Advanced Materials·Jihyeon YeomAna Jaklenec
Aug 29, 2020·Physical Review Letters·Jorge Olmos-TrigoJuan José Sáenz
Oct 3, 2020·International Journal of Molecular Sciences·Anastasia NazarovaIvan Stoikov
Dec 30, 2020·Proceedings of the National Academy of Sciences of the United States of America·Jincheng NiCheng-Wei Qiu
Aug 28, 2020·ACS Nano·Taeko MatsukataTakumi Sannomiya
May 10, 2020·Nano Letters·Tyler R HarveyClaus Ropers
Jun 25, 2021·ACS Photonics·Ershad MohammadiAlberto G Curto
Jul 13, 2021·Nano Letters·Mariachiara ManoccioAdriana Passaseo
Jul 2, 2020·Nano Letters·Sotiris Droulias, Lykourgos Bougas
Mar 18, 2020·Nano Letters·Ranran ZhangWing Yim Tam
Oct 23, 2020·ACS Applied Materials & Interfaces·Yuduo GuanGang Zhang
Dec 19, 2019·Nano Letters·Jose García-GuiradoRomain Quidant
Jan 9, 2020·Accounts of Chemical Research·Michelle L SolomonJennifer A Dionne
Oct 14, 2020·Journal of the American Chemical Society·Michelle L SolomonJennifer A Dionne
Nov 21, 2020·Nano Letters·Yang ChenCheng-Wei Qiu
Sep 3, 2021·Light, Science & Applications·Jungho MunJunsuk Rho
Oct 6, 2021·ACS Nano·Lauren A WarningStephan Link
Dec 1, 2021·ACS Nano·Maryam HajjiMalcolm Kadodwala

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