PMID: 2271658Nov 20, 1990

Enantioselective oxidations of sulfides catalyzed by chloroperoxidase

Biochemistry
S ColonnaP Pasta

Abstract

The chloroperoxidase-catalyzed and horseradish peroxidase catalyzed oxidations of sulfides by tert-butyl and other peroxides have been investigated. The former metal enzyme afforded the corresponding sulfoxides having R absolute configuration in up to 92% enantiomeric excess (ee), whereas the latter gave racemic products. The various factors that control the enantioselectivity of the oxygenation have been examined.

References

Aug 11, 1987·Biochemistry·S KobayashiA P Schaap
May 6, 1986·Biochemistry·O BangcharoenpaurpongLowell P Hager
Feb 26, 1986·Biochemical and Biophysical Research Communications·S KobayashiA P Schaap

Citations

Sep 19, 2000·Biotechnology and Bioengineering·L Dai, Alexander M Klibanov
Apr 22, 2006·Applied Microbiology and Biotechnology·Martin Hofrichter, René Ullrich
Oct 31, 2001·Phytochemistry·R Vázquez-DuhaltF J Márquez-Rocha
Jun 19, 2001·Biochimica Et Biophysica Acta·Kelath M Manoj, Lowell P Hager
Apr 17, 1999·Trends in Biotechnology·S ColonnaP Pasta
Aug 29, 2003·Current Opinion in Biotechnology·Alexander M Klibanov
Dec 12, 2001·Current Opinion in Chemical Biology·D L Harris
Feb 18, 1999·Current Opinion in Chemical Biology·J Littlechild
Apr 11, 2006·Organic & Biomolecular Chemistry·Franck DaligaultHenri Patin
Oct 30, 2009·Organic & Biomolecular Chemistry·H M de HoogI W C E Arends
Dec 20, 2000·European Journal of Biochemistry·A CelikE L Raven
Jul 3, 2007·Applied and Environmental Microbiology·Dau Hung AnhMartin Hofrichter
May 22, 2007·BMC Biotechnology·Jian-Zhong Liu, Min Wang
Nov 12, 1996·Proceedings of the National Academy of Sciences of the United States of America·P G DebrunnerLowell P Hager
Oct 27, 1999·Proceedings of the National Academy of Sciences of the United States of America·X YiLowell P Hager
Jul 31, 2014·Applied Microbiology and Biotechnology·Toru MatsuiMakoto Ueda
Sep 1, 2011·Organic & Biomolecular Chemistry·Viktor MojrTomáš Kraus
Mar 2, 2016·Archives of Biochemistry and Biophysics·Rui ZhangXiaotang Wang
Mar 15, 2012·Chembiochem : a European Journal of Chemical Biology·Chantel N JensenGideon Grogan
Aug 15, 1992·Archives of Biochemistry and Biophysics·C Hartmann, P R Ortiz de Montellano
Jan 8, 1999·Biochemical and Biophysical Research Communications·S Hu, Lowell P Hager
Jan 24, 2012·Archives of Biochemistry and Biophysics·Eugene G Hrycay, Stelvio M Bandiera
Feb 11, 2003·The Journal of Biological Chemistry·Xianwen YiLowell P Hager
Jun 23, 2006·The Journal of Biological Chemistry·Karin KühnelIlme Schlichting
Dec 19, 2002·The Journal of Biological Chemistry·Xiaotang WangLowell P Hager

Related Concepts

Chloride Peroxidase
Alpha-Peroxidase
Oxidation-Reduction
Molecular Stereochemistry
Substrate Specificity
Thioethers
Sulfoxides

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