Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system.

Beilstein Journal of Organic Chemistry
Caterina FraschettiJochen Mattay

Abstract

This review describes the state-of-art in the field of the gas-phase reactivity of diastereomeric complexes formed between a chiral artificial receptor and a biologically active molecule. The presented experimental approach is a ligand-displacement reaction carried out in a nano ESI-FT-ICR instrument, supported by a thermodynamic MS-study and molecular-mechanics and molecular-dynamics (MM/MD) computational techniques. The noncovalent ion-molecule complexes are ideal for the study of chiral recognition in the absence of complicating solvent and counterion effects.

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Citations

Jun 20, 2016·Journal of Chromatography. a·Gerhard K E Scriba
Apr 12, 2017·Analytica Chimica Acta·Xiangying Yu, Zhong-Ping Yao
Feb 17, 2018·Chirality·Xiaolei ChenSu Zeng
Oct 31, 2017·Mass Spectrometry Reviews·Dirk NoltingAlexander Makarov
Mar 1, 2014·European Journal of Mass Spectrometry·James C ReynoldsHarry Heaney
Jul 20, 2017·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Antonello FilippiMaurizio Speranza
Jan 28, 2021·Journal of the American Society for Mass Spectrometry·Caterina FraschettiAntonello Filippi

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Methods Mentioned

BETA
NMR

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