Encephalitozoon cuniculi-associated placentitis and perinatal death in an alpaca (Lama pacos)

Veterinary Pathology
J D WebsterR Vemulapalli

Abstract

Placentitis, premature birth, and perinatal death were associated with Encephalitozoon cuniculi infection in an alpaca. Histologically, chorionic trophoblasts contained many Gram-positive, period acid-Schiff positive, variably acid-fast spores. Multifocal necrosis and infiltration by lymphocytes, eosinophils, and neutrophils were scattered throughout the chorionic membrane. Spores in trophoblasts were approximately 1 microm x 2 microm, thick-walled, and contained polar filaments and polar vacuoles consistent with microsporidia. The presence of E. cuniculi DNA was confirmed by sequencing the polymerase chain reaction amplicon from frozen placental tissue. A few glial nodules were scattered throughout the cerebrum, and mild lymphocytic inflammation was present in the heart, liver, and lung. No organisms were detected in tissues other than the placenta. This is the first reported case of E. cuniculi infection in an alpaca.

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Citations

Jul 1, 2009·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Leslie McPhersonRichard R Dubielzig
May 7, 2019·Reproduction in Domestic Animals = Zuchthygiene·Maya MeestersJan Govaere
Nov 11, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Roberto RomeroLami Yeo
Nov 26, 2013·African Journal of Laboratory Medicine·Amase NyamngeeDouglas B Moser
Sep 25, 2010·The Veterinary Record·C A BidewellS M Williamson
May 1, 2021·Pathogens·Pavel KvapilEva Bártová

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Methods Mentioned

BETA
ELISA
PCR

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