Encephalopathy associated with influenza A

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society
Martijn H SmidtMarcel Peeters

Abstract

We report a 3-year-old boy with influenza A virus-associated encephalopathy. The diagnosis was based on clinical findings, magnetic resonance imaging, repeated isolation of influenza A virus from nasopharyngeal aspirate and seroconversion between acute and convalescent sera. The clinical picture was characterized by fever and aphasia followed by seizures and a rapid deterioriation of consciousness 2 days later. This patient illustrates that influenza A-associated encephalopathy with severe neurological deficit can occur with atypical distribution of brain lesions during the course of the illness, while initial brain MRI and laboratory findings of cerebrospinal fluid are normal, including reverse transcription polymerase chain reaction.

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Citations

Aug 15, 2012·Seminars in Pediatric Neurology·Jeffrey J Ekstrand
Sep 3, 2010·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·M Jequier GygaxE Roulet-Perez
Oct 13, 2009·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Joel FlussMaria Isabel Vargas
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May 20, 2008·Travel Medicine and Infectious Disease·Stephen Toovey
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Jan 24, 2007·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·I-Jen WangWang-Tso Lee
Mar 18, 2009·Microbiology and Immunology·Tomoaki WadaYoshinobu Okuno
Feb 11, 2005·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·V Dubowitz
Sep 7, 2005·Journal of the Neurological Sciences·Takashi IchiyamaSusumu Furukawa
May 11, 2010·Current Opinion in Neurology·Gefei F WangKangsheng Li
May 8, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Takeshi HatachiHideo Yasunaga
Nov 5, 2008·Expert Review of Vaccines·Takeshi IchinoheHideki Hasegawa
Oct 12, 2020·BMJ Case Reports·Reiichiro Obata, Kristina Ernst

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