Encoding of Articulatory Kinematic Trajectories in Human Speech Sensorimotor Cortex

Neuron
Josh ChartierEdward F Chang

Abstract

When speaking, we dynamically coordinate movements of our jaw, tongue, lips, and larynx. To investigate the neural mechanisms underlying articulation, we used direct cortical recordings from human sensorimotor cortex while participants spoke natural sentences that included sounds spanning the entire English phonetic inventory. We used deep neural networks to infer speakers' articulator movements from produced speech acoustics. Individual electrodes encoded a diversity of articulatory kinematic trajectories (AKTs), each revealing coordinated articulator movements toward specific vocal tract shapes. AKTs captured a wide range of movement types, yet they could be differentiated by the place of vocal tract constriction. Additionally, AKTs manifested out-and-back trajectories with harmonic oscillator dynamics. While AKTs were functionally stereotyped across different sentences, context-dependent encoding of preceding and following movements during production of the same phoneme demonstrated the cortical representation of coarticulation. Articulatory movements encoded in sensorimotor cortex give rise to the complex kinematics underlying continuous speech production. VIDEO ABSTRACT.

Citations

Dec 28, 2019·JAMA : the Journal of the American Medical Association·Edward F Chang, Gopala K Anumanchipalli
May 10, 2019·Cerebral Cortex·Niels Janssen, Cristian Camilo Rincón Mendieta
Sep 4, 2019·PLoS Computational Biology·Benjamin ParrellJohn Houde
Feb 28, 2020·Nature Communications·Arnaud ZaltaBenjamin Morillon
Mar 1, 2020·Scientific Reports·Niels JanssenHoracio A Barber
May 8, 2020·Nature Reviews. Neuroscience·David Poeppel, M Florencia Assaneo
Apr 26, 2019·Nature·Gopala K AnumanchipalliEdward F Chang
Apr 26, 2020·American Journal of Speech-language Pathology·Christopher NightingaleTara McAllister
Apr 26, 2019·Nature·Chethan Pandarinath, Yahia H Ali
Feb 13, 2020·Frontiers in Psychology·Aravind Kumar NamasivayamPascal van Lieshout
Aug 1, 2019·Nature Communications·David A MosesEdward F Chang
Sep 10, 2020·BMC Biomedical Engineering·Wing-Kin TamZhi Yang
Jan 11, 2020·Frontiers in Psychology·Louis Goldstein
Nov 26, 2020·Journal of Neural Engineering·Guy H WilsonKrishna V Shenoy
Nov 4, 2020·Journal of Neural Engineering·Pengfei SunEdward F Chang
Jan 29, 2021·Cerebral Cortex Communications·Shihab ShammaNima Mesgarani
Dec 8, 2019·World Neurosurgery·Evelyn L TurcotteBernard R Bendok
Jul 22, 2019·Current Opinion in Neurobiology·Bingni W Brunton, Michael Beyeler
Mar 21, 2021·Seminars in Neurology·Michael J YoungLeigh R Hochberg
Sep 14, 2019·Neuroscience and Biobehavioral Reviews·Benjamin MorillonAnne Keitel
Sep 6, 2020·Current Biology : CB·Matthew K LeonardEdward F Chang
May 21, 2021·Nature·Tejapratap BolluJesse H Goldberg
Jun 18, 2021·Current Biology : CB·Ezequiel M ArneodoTimothy Q Gentner
Jul 15, 2021·The New England Journal of Medicine·David A MosesEdward F Chang
Aug 24, 2021·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Aniruddh D Patel
Sep 2, 2021·Cerebral Cortex·C Dastolfo-HromackR M Richardson
Nov 11, 2021·Proceedings of the National Academy of Sciences of the United States of America·Alexander A AabediShawn L Hervey-Jumper

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