End of day dyskinesia in advanced Parkinson's disease can be eliminated by bilateral subthalamic nucleus or globus pallidus deep brain stimulation

Movement Disorders : Official Journal of the Movement Disorder Society
Diana ApetauerovaDaniel Tarsy

Abstract

We report the therapeutic effects of deep brain stimulation (DBS) in 2 patients with Parkinson's disease (PD) with severe end of dose dyskinesia that was resistant to medical therapy. In both patients, severe, end of day ballistic dyskinesias occurred when the last levodopa dose of the day was wearing off. Globus pallidus (GPi) DBS in 1 case and subthalamic (STN) DBS in the second case produced full resolution of end of day dyskinesia.

References

Jan 1, 1992·Movement Disorders : Official Journal of the Movement Disorder Society·M R LuquinJ A Obeso
Mar 1, 1994·Movement Disorders : Official Journal of the Movement Disorder Society·T R ZimmermanM H Mark
Mar 4, 1998·Annals of Neurology·P KrackA L Benabid
Sep 29, 2001·The New England Journal of Medicine·UNKNOWN Deep-Brain Stimulation for Parkinson's Disease Study GroupA E Lang
Sep 5, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·Karen ØstergaardErik Dupont

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Citations

Aug 23, 2011·Neuromodulation : Journal of the International Neuromodulation Society·Ludy C ShihDaniel Tarsy
Apr 19, 2011·Nonlinear Biomedical Physics·Alberta LatteriPaolo Mazzone
Mar 17, 2020·Journal of Neural Transmission·Roongroj BhidayasiriClaudia Trenkwalder
Mar 30, 2021·Frontiers in Neuroscience·Kai YangTaolei Sun
May 11, 2021·Journal of Parkinson's Disease·Milan BeckersBastiaan R Bloem

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