End-of-life care for persons with advanced Alzheimer disease: design and baseline data from the ALFINE study.

The Journal of Nutrition, Health & Aging
F NourhashémiY Rolland

Abstract

Alzheimer disease (AD) is the most common cause of dementia. Most affected individuals survive to an advanced stage of dementia, which is under-recognized as a terminal illness. Our objectives were to better understand the clinical trajectory of advanced AD and to identify the palliative care needs of these patients. This was an observational prospective study of AD patients in severe stage of disease included after a hospitalization in geriatric wards. They were followed up every three months during 2 years. At each visit, interviews provided data regarding: pain (Elderly Pain Caring Assessment scale), pressure ulcers, eating patterns, daily medications and use of health services. This paper describes the design of the ALFINE study and the characteristics of the recruited cohort. 112 patients were recruited (mean age: 84.03 + 6.96) years; 76.79% were women. Mean time since diagnosis of AD was 5.28 years. Pressure ulcers were observed in 42 patients. Pain assessment with the EPCA showed a mean score of 8.58. One third of patients with an EPCA score of more than 7 (median) had no analgesics. More than half of patients had been treated with antibiotics during the three months before inclusion in the study and 33 patients were sti...Continue Reading

References

Jun 20, 1990·JAMA : the Journal of the American Medical Association·K J FabiszewskiL Volicer
Jan 1, 1990·World Health Organization Technical Report Series
Sep 1, 1990·Archives of Dermatology·G M YarkonyH B Betts
Jun 1, 1986·The Gerontologist·S H ZaritJ M Zarit
Jun 11, 1999·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·S M AlbertY Stern
Oct 20, 1999·JAMA : the Journal of the American Medical Association·T E FinucaneK Travis
May 9, 2000·Journal of Pain and Symptom Management·R S Morrison, A L Siu
Jun 29, 2000·JAMA : the Journal of the American Medical Association·R S Morrison, A L Siu
Oct 25, 2000·International Journal of Geriatric Psychiatry·A WimoM Grafström
May 26, 2001·Clinics in Geriatric Medicine·L Volicer
May 15, 2003·JAMA : the Journal of the American Medical Association·June R LunneyJack M Guralnik
Jun 6, 2003·The American Journal of Hospice & Palliative Care·Ladislav VolicerZuzka V Blasi
Sep 21, 1963·JAMA : the Journal of the American Medical Association·S KATZM W JAFFE
Feb 11, 2004·Archives of Internal Medicine·Susan L MitchellMary Beth Hamel
Oct 16, 2004·Journal of General Internal Medicine·Greg A SachsDeon Cox-Hayley
Aug 5, 2005·Journal of the American Geriatrics Society·Jennifer L LambergSusan L Mitchell
Jan 12, 2008·BMJ : British Medical Journal·Jing XieUNKNOWN Medical Research Council Cognitive Function and Ageing Study collaborators
May 17, 2008·Journal of the American Geriatrics Society·Holly M HolmesWilliam Dale
Jan 27, 2009·Medical Care·Joseph E GauglerJean F Wyman
May 12, 2009·Journal of the American Medical Directors Association·Sylvia KuoJoan M Teno
Jul 2, 2009·The British Journal of Psychiatry : the Journal of Mental Science·Elizabeth L SampsonMichael King
Aug 19, 2009·International Journal of Geriatric Psychiatry·Claire GoodmanSteve Iliffe
Aug 22, 2009·Acta Psychiatrica Scandinavica·W QuentinH-H König
Sep 1, 2009·Journal of the American Medical Directors Association·Michelle Lee, Joshua Chodosh
Sep 24, 2009·International Journal of Palliative Nursing·Bridget CandyLouise Jones
Oct 16, 2009·The New England Journal of Medicine·Susan L MitchellMary Beth Hamel
Oct 27, 2009·Archives of Gerontology and Geriatrics·O ZanettiF Cantoni
Jan 13, 2010·Archives of Internal Medicine·Ruth Palan LopezSusan L Mitchell
Feb 4, 2010·The Journal of Nutrition, Health & Aging·D GoveI Holmerova
Feb 11, 2010·JAMA : the Journal of the American Medical Association·Joan M TenoVincent Mor
Jul 10, 2010·The Journal of Nutrition, Health & Aging·S J TorresC A Nowson
Aug 3, 2010·British Medical Bulletin·Elizabeth L Sampson
Sep 18, 2010·Journal of Alzheimer's Disease : JAD·Jenny T van der Steen

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Citations

Nov 12, 2014·Drugs & Aging·Tessa van der MaadenJenny T van der Steen
Jul 28, 2016·Dementia·Elizabeth HansonDebbie Tolson
Apr 3, 2020·Nursing Older People·Margaret Brown, Debbie Tolson
May 28, 2019·Journal of Alzheimer's Disease : JAD·Gaëtane PicardAdrian Ivanoiu
Nov 12, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Alexandre R MarraEli N Perencevich
Dec 2, 2020·BMJ Supportive & Palliative Care·Jack FairweatherR Andrew Seaton
Apr 23, 2021·International Journal of Palliative Nursing·Grainne McAneeGerry Leavey

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