End-of-life palliative chemotherapy: where do we stand?

Journal of the Egyptian National Cancer Institute
Amrallah A MohammedHani M El-Khatib

Abstract

This study evaluates the use of palliative chemotherapy (PCT) and possible associated factors at the end of life. The study includes all advanced non hematological cancer patients who died in the King Abdullah Medical City during the period from January 2011 to April 2014. Demographic and disease features were registered. 420 patients were included in the study, median age 62 years (range 17-108); 52% female and 48% male. 87.4% of patients were Saudis and 12.6% non Saudis. 124 (29.5%) patients received PCT at the last month before death (LM-PCT): 21.8%, 22.6% and 55.6% within one, two and four weeks of death, respectively. Place of death (critical care vs. regular ward) and mode of admission (ER vs. OPD vs. Transferred) had a strong association with LM-PCT (p<0.0001, ϕ=0.35) and (p<0.0001, V=0.43), respectively. There was a gradual increase in the number of patients receiving LM-PCT from January 2011 to April 2014; 15.3%, 28.2%, 37.1% and 19.4%, respectively. In our center; at the end of life, there is a gradual increase in the number of patients receiving chemotherapy which significantly increased cancer patients' odds without clear predictive factors associated with its use, which calls into question the benefits of PCT in te...Continue Reading

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Citations

Sep 24, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Tarek AssiJoseph Kattan
May 17, 2018·Journal of Palliative Medicine·Sudha SinhaMikael Segerlantz
Dec 12, 2018·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Tomo AndoCindy L Grines
Nov 2, 2019·Indian Journal of Palliative Care·Amrallah A MohammedFifi Mostafa Elsayed
May 27, 2021·Indian Journal of Palliative Care·Amrallah A MohammedAyman Elshentenawy

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