End-stage renal failure due to crescentic glomerulonephritis in a patient with Behçet's syndrome. Review of the literature

American Journal of Nephrology
T SakemiK Nagasawa

Abstract

We report a rare case of a patient with Behçet's syndrome who developed end-stage renal failure due to crescentic glomerulonephritis (GN). A 20-year-old male patient had suffered from uveitis, aphthous mouth ulcers and genital ulceration for the past 7 years. His renal function rapidly deteriorated and renal biopsy specimens obtained when his serum creatinine level was 3 mg/dl showed diffuse proliferative GN with fibrous crescent formation in 75% of glomeruli excluding totally sclerotic glomeruli. Immune complexes were identified by demonstration of complement and immunoglobulins in the glomeruli. He developed end-stage renal failure during a 1-year course and received maintenance hemodialysis. We reviewed the literature on severe forms of GN in patients with Behçet's syndrome.

Citations

Nov 10, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Seza Ozen
Aug 16, 2016·Internal Medicine·Duriye Deren Oygar, Yonca Morris
Jan 23, 1999·Current Opinion in Rheumatology·H YaziciV Hamuryudan
Apr 20, 2002·Seminars in Arthritis and Rheumatism·Tekin AkpolatSeza Ozen

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