Endobronchial metastases from melanoma: a survival analysis

The Clinical Respiratory Journal
Amandine ChaussendeJean-Michel Vergnon

Abstract

Metastatic spread to the tracheobronchial tree from other than bronchopulmonary tumors is a common clinical problem. However, malignant melanoma, a highly metastatic potential tumor, is rarely metastasing in the airways. Therefore little is known about survival of patients with endobronchial metastasis from melanoma. The aim of our study was to assess survival of patients with endobronchial metastasis of melanomas according to clinical and radiological features, to determine any possible factor affecting survival. This retrospective study included 19 patients who underwent a bronchoscopy from 11 different hospitals. Data about patients' demographics, symptoms, radiographic, endoscopic findings and treatment were investigated to evaluate any possible impact on survival. Endobronchial metastases occurred at a median of 48 months (range 0-120) following the diagnosis of the primary tumor. About 73.7% of patients had other proven metastases when the endobronchial involvement was diagnosed. Symptoms are not specific as well as radiological features. Median overall survival of the studied population was 6 months (range 1-46). Factors of poor survival were multiple metastatic sites (P = 0.019), pleural (P = 0.0014) and soft tissue met...Continue Reading

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Citations

Jul 18, 2020·Curēus·Marium GhaniAlfred Papali
May 10, 2019·BMJ Case Reports·Grace Nabila Martinez Pena, Chuan Jiang
Feb 15, 2021·Revue des maladies respiratoires·N GuibertJ-M Vergnon

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