PMID: 8944738Nov 25, 1996Paper

Endocarditis in an urban hospital in the 1990s

Archives of Internal Medicine
S SiddiqD I Silverman

Abstract

To analyze the clinical characteristics and outcome of 159 consecutive patients with endocarditis who presented to an inner-city hospital from 1990 onward and to elucidate the most current problems and advances in the management of endocarditis. One hundred eighty-two consecutive cases (in 159 patients) met diagnostic criteria for endocarditis, including histopathologic evidence or multiple positive blood cultures without another primary source, and appropriate signs or symptoms. Transthoracic echocardiography was performed for 171 cases, and 36 patients underwent transesophageal echocardiography. Sixty-seven percent of the patients were known drug users; more than 80% of these were positive for human immunodeficiency virus. Fever, malaise, and fatigue occurred in more than 95%, but other signs were neither sensitive nor specific, and classic microvascular phenomena were uncommon. Blood cultures were positive in 96%, all 7 patients with negative cultures had received prior antibiotic therapy. Staphylococcus aureus was the most common organism, and a significant increase in S aureus infections was noted for tricuspid endocarditis (chi 2 = 71.07, P = .003). The mitral (n = 51) and tricuspid (n = 49) valves were the most common si...Continue Reading

Citations

Jun 21, 2005·Current Infectious Disease Reports·Michael J Wahl, Thomas J Pallasch
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Jul 27, 2002·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Inmaculada Tomás CarmonaCrispian Scully
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