PMID: 11915579Mar 28, 2002Paper

Endocrine function in HIV-infected women

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
S HinzZ M van der Spuy

Abstract

Infection with the human immunodeficiency virus (HIV) results in a chronic systemic illness with multi-organ involvement, severe immunosuppression and profound cachexia. It has had a major impact on women's health. Endocrine abnormalities may contribute to the clinical presentation and therefore appropriate treatment would theoretically improve the patient's condition. This pilot study was undertaken to assess the endocrine status in a group of HIV seropositive women with the view to developing recommendations for future investigations. Thirteen women were recruited from a clinic for HIV-infected patients. All women had a comprehensive general and gynecological examination. Basal endocrine status was assessed and combined pituitary testing with gonadotropin-releasing hormone, thyrotropin-releasing hormone, growth hormone-releasing hormone and corticotropin-releasing hormone was performed. None of the participating women presented with gynecological complaints or had symptoms suggestive of an endocrinopathy. On questioning, seven women complained of menstrual abnormalities. Three had a body mass index of less than 20 kg/m2. Genital tract infections were common. Endocrine assessment demonstrated abnormalities of the pituitary-adr...Continue Reading

Citations

Dec 17, 2008·Women's Health·Augusto Enrico SempriniCarole Gilling-Smith
Jun 27, 2006·Journal of Women's Health·L Stewart MassadMardge Cohen
Feb 18, 2006·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·William F Paolo, Joshua D Nosanchuk
Nov 14, 2012·Human Reproduction Update·V SavasiI Cetin
Dec 18, 2010·Archives of Gynecology and Obstetrics·Andrea GingelmaierKatharina Weizsaecker

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