Nov 8, 2016

Endocrine-reproductive-immune interactions in female and male Galápagos marine iguanas

Hormones and Behavior
Lorin A Neuman-Lee, Susannah S French

Abstract

Endocrine-immune interactions are variable across species and contexts making it difficult to discern consistent patterns. There is a paucity of data in non-model systems making these relationships even more nebulous, particularly in reptiles. In the present study, we have completed a more comprehensive test of the relationship among steroid hormones and ecologically relevant immune measures. We tested the relationship between baseline and stress-induced levels of sex and adrenal steroid hormones and standard ecoimmunological metrics in both female and male Galápagos marine iguanas (Amblyrhynchus cristatus). We found significant associations between adrenal activity and immunity, whereby females that mounted greater corticosterone responses to stress had lower basal and stress-induced immunity (i.e., bactericidal ability). Males showed the opposite relationship, suggesting sex-specific immunomodulatory actions of corticosterone. In both sexes, we observed a stress-induced increase in corticosterone, and in females a stress-induced increase in bactericidal ability. Consistent with other taxa, we also found that baseline corticosterone and testosterone in males was inversely related to baseline bactericidal ability. However, in f...Continue Reading

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Citations

Mentioned in this Paper

Serum Hormone Levels (Lab Test)
Corticosterone Assay
Study
Immune Response
Immune System
Testosterone Measurement
Biological Adaptation to Stress
Complement Activity
Patterns
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