Endocrine xenoestrogenics disrupters: molecular mechanisms and detection methods

Thérapie
Wissem MnifAghleb Bartegi

Abstract

The attention paid to endocriniens modulators for purpose micropolluants (endocrine disrupters) has been increasingly studied these last years particularly on animals. The results of this study raised big concerns from Doctors and Biologists on the eventual risks human health can face. Indeed, endocrine systems of the body play an essential and pervasive role in both the short- and long-term regulation of metabolic processes. Nutritional, behavioural, and reproductive processes are intricately regulated by endocrine systems, as are growth (including bone growth/remodelling), gut, cardiovascular, and kidney function and responses to all forms of stress. Disorders of any of the endocrine system, involving both over- and under-active hormone secretion, result inevitably in disease, the effects of which may extend to many different organs and functions and are often debilitating or life-threatening. Viewed from this general perspective, the threat posed from environmental chemicals with endocrine activity (either agonist or antagonistic) is potentially serious. However, the fact that humans and wildlife are exposed to such chemicals does not necessarily mean that clinically manifest disturbance of the relevant endocrine system will...Continue Reading

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Citations

Jul 22, 2011·International Journal of Environmental Research and Public Health·Wissem MnifBenoit Roig
Dec 4, 2012·International Journal of Environmental Research and Public Health·Eva Matisová, Svetlana Hrouzková
Feb 22, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Hyekyoung Hannah You, Gwonhwa Song

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