ENDOCRINOLOGY AND ADOLESCENCE: Dealing with transition in young patients with pituitary disorders

European Journal of Endocrinology
Emilia SbardellaAshley B Grossman

Abstract

The transition age is the period between childhood to adulthood; it refers to a broad set of physical, cognitive and sociocultural modifications, arbitrarily defined as starting in late puberty and ending with full adult maturation. Pituitary disorders in adolescence represent a challenge that requires careful management during the transition to adult care. Given the complexity of care of pituitary disorders in the transition age, we have reviewed the relevant medical literature focusing on aetiology, clinical manifestations, treatment strategies of GH deficiency (GHD), hypogonadotrophic hypogonadism (HH) in male and female adolescents, central hypothyroidism (CH), central adrenal insufficiency (CAI) and cranial diabetes insipidus (CDI) at this time. The objective of the present review is to provide an up-to-date evaluation of the transition period to evaluate the specific needs of adolescents with chronic pituitary disease in order to optimise their management. We provide an overview of current clinical management of GHD, HH, CH, CAI and CDI in the transition age. Specific changes occur in pituitary function during the transition period. A holistic approach including discussion of patients' concerns and emotional support shoul...Continue Reading

Citations

Jun 4, 2020·Pituitary·Emilia SbardellaAshley B Grossman
Nov 28, 2019·Journal of Endocrinological Investigation·A M IsidoriUNKNOWN Italian Society of Endocrinology
Oct 9, 2020·Reviews in Endocrine & Metabolic Disorders·Margaret C S Boguszewski
Oct 14, 2020·Minerva pediatrica·Sergio Bernasconi
Oct 24, 2020·Journal of Endocrinological Investigation·G GrugniUNKNOWN Genetic Obesity Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED)
May 21, 2021·Journal of Medical Internet Research·Paul DimitriEkaterina Koledova
Jun 18, 2021·Journal of Neuroendocrinology·Emilia SbardellaUNKNOWN Talent group
Mar 30, 2021·The Journal of Clinical Endocrinology and Metabolism·Jolanda C NaafsNitash Zwaveling-Soonawala
Apr 27, 2020·Neuroendocrinology·Emilia SbardellaAndrea M Isidori

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