Endogenous estrogen may prevent bone loss in postmenopausal hemodialysis patients throughout life.

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
N SugiyaNoriaki Yorioka

Abstract

Postmenopausal hemodialysis patients are at risk of complications related to renal mineral and bone disorder, and postmenopausal osteoporosis. In 112 postmenopausal hemodialysis patients, free estrogen index was positively correlated with bone mineral density (BMD) Z-score and the annual percent change of BMD in multiple regression analysis. Endogenous estrogen may prevent bone loss in postmenopausal hemodialysis patients throughout life. Women on dialysis are not only at risk of developing mineral and bone disorder, but also suffer from postmenopausal osteoporosis. We assessed the effect of sex hormones on bone metabolism in postmenopausal hemodialysis patients. We enrolled 112 postmenopausal hemodialysis patients with a mean age of 68.4 ± 10.4 years. We measured the serum levels of estradiol, testosterone, sex hormone-binding globulin (SHBG), and intact parathyroid hormone (intact-PTH), as well as bone metabolism parameters and radial bone mineral density (BMD). The free estrogen index (FEI) was calculated from the estradiol and SHBG values. After conventional dialysis was performed for 12 months, BMD was measured again and the annual percent change was calculated. Estradiol and SHBG were also measured in 25 postmenopausal wo...Continue Reading

References

Dec 1, 1992·The Journal of Clinical Investigation·T Naveh-ManyJ Silver
Jan 1, 1992·Maturitas·S M McKinlayJ G Posner
Nov 1, 1990·Annals of Clinical Biochemistry·C Selby
Nov 1, 1990·The Journal of Clinical Endocrinology and Metabolism·C GennariR Civitelli
Apr 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R PacificiW A Peck
Mar 1, 1988·The Journal of Clinical Endocrinology and Metabolism·B DuarteS C Kukreja
Dec 15, 1973·British Medical Journal·R B PayneJ R Milner
May 1, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J L HolleyM Schiff
Jul 8, 2000·Kidney International·J R WeisingerE Bellorín-Font
Nov 22, 2001·Proceedings of the National Academy of Sciences of the United States of America·C RoggiaR Pacifici
Jul 19, 2002·JAMA : the Journal of the American Medical Association·Jacques E RossouwUNKNOWN Writing Group for the Women's Health Initiative Investigators
May 28, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Ayumu NakashimaSatoru Harada
May 31, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Holly Mattix KramerUNKNOWN HELP Study Group
Dec 22, 2005·Journal of Bone and Mineral Metabolism·Irene LambrinoudakiGeorge Creatsas
Jan 6, 2006·Environmental Health Perspectives·Paloma Alonso-MagdalenaAngel Nadal
Aug 3, 2006·The Journal of Clinical Endocrinology and Metabolism·Jennifer S LeeSteven R Cummings
Jan 25, 2007·The Journal of Clinical Endocrinology and Metabolism·Sherita Hill GoldenPamela Ouyang

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Citations

Aug 6, 2013·Journal of Atherosclerosis and Thrombosis·Ozkan GungorErcan Ok
Apr 15, 2014·Arthritis Research & Therapy·Martin SchichtHorst Claassen
Apr 25, 2012·International Urology and Nephrology·Mehmet TanrisevErcan Ok
Aug 24, 2013·Acupuncture in Medicine : Journal of the British Medical Acupuncture Society·Han LiYinping Wang
Jul 22, 2016·Prilozi·Piotr KuczeraAndrzej Wiecek
Oct 16, 2018·Current Opinion in Nephrology and Hypertension·José Manuel ValdivielsoMaría José Soler
Sep 28, 2018·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Yukitoshi SakaoHideo Yasuda
Nov 1, 2016·Expert Review of Endocrinology & Metabolism·Rathika KrishnasamyDavid W Johnson
Feb 16, 2021·Calcified Tissue International·Hanne Skou JørgensenUNKNOWN European Renal Osteodystrophy (EUROD) workgroup, an initiative of the CKD-MBD working group of the ERA-EDTA

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