PMID: 13563800Jul 20, 1958Paper

Endogenous photosensitization in a carotenoidless mutant of Rhodopseudomonas speroides

The Journal of General Physiology
M DWORKIN

Abstract

Endogenous photosensitization in a carotenoidless mutant of Rhodopseudomonas spheroides has been studied. When this mutant is exposed to visible light and oxygen there is a short lag period followed by exponential killing of the cells. The killing process obeys the Bunsen-Roscoe law of reciprocity and is temperature-independent. The chlorophyll content of the cells does not affect the rate of killing until a certain low threshold has been reached. Exposure of photosynthetically grown cells to air in the dark induces a temporary desensitization to the killing. A certain proportion of the population is invariably resistant to the photokilling. Evidence is presented to show that the resistance of these cells is probably a result of their abnormally low chlorophyll content. One consequence of the irradiation is the appearance of abnormally small colonies upon plating the survivors. This is interpreted in terms of a multi-hit theory. The photosensitizing pigment itself (the intracellular bacteriochlorophyll) is destroyed. The process is zero order, temperature-dependent, and does not follow the reciprocity law. It is suggested that the death of the cell results from a disruption of the cell membrane.

References

Dec 24, 1955·Nature·M GRIFFITHSM CALVIN
Jan 1, 1956·Archiv für Mikrobiologie·R W KAPLAN
Jul 1, 1956·Journal of General Microbiology·M GRIFFITHS, R Y STANIER
Dec 1, 1956·Journal of Cellular Physiology·W R SISTROMR Y STANIER
Feb 1, 1957·Journal of Cellular Physiology·G COHEN-BAZIRER Y STANIER
Sep 1, 1957·Archives of Biochemistry and Biophysics·J W NEWTON, G A NEWTON

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Citations

Jan 1, 1962·Archiv für Mikrobiologie·S BENDIX, M B ALLEN
Jan 1, 1971·Archiv für Mikrobiologie·U Eberhardt
Jan 1, 1960·Archiv für Mikrobiologie·M M MATHEWS, W R SISTROM
Mar 1, 1971·Photochemistry and Photobiology·W A Maxwell, C O Chichester
Feb 18, 2015·Future Microbiology·Steven L PercivalGianfranco Donelli
Dec 25, 2016·Environmental Toxicology and Chemistry·Solmaz Marzooghi, Dominic M Di Toro
Dec 23, 2011·Brazilian Dental Journal·Fernanda G BassoCarlos A de Souza Costa
Jan 1, 1986·Lasers in Surgery and Medicine·R J SchultzF Cabello
Jul 1, 1966·Photochemistry and Photobiology·J D MacmillanC O Chichester
Aug 24, 2016·Environmental Toxicology and Chemistry·Solmaz MarzooghiDominic M Di Toro
Jul 1, 1977·CRC Critical Reviews in Microbiology·D E Caldwell, J Overbeck
Jul 22, 2019·Lasers in Medical Science·Lidija NemethKsenija Cankar
Jan 1, 1996·Lasers in Surgery and Medicine·Y AndoI Ishikawa
Mar 1, 1977·Bacteriological Reviews·L Barksdale, K S Kim
Sep 1, 1984·Microbiological Reviews·R F Taylor
Jan 4, 1980·Biochimica Et Biophysica Acta·K BauerW Seiler
Aug 1, 1959·Archives of Biochemistry and Biophysics·J W NEWTON, L LEVINE
May 25, 1964·Biochimica Et Biophysica Acta·R S HANSON

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