Endoluminal formalin application for haemorrhagic radiation proctitis

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
F L VyasS R Banerjee Jesudason

Abstract

Radiation proctitis is a common complication following radiation therapy for pelvic malignancies. This is associated with significant morbidity which adversely affects the quality of life. Local application of formalin has been used effectively in the treatment of radiation proctitis. Thirty patients with haemorrhagic radiation proctitis who underwent endoluminal application of 4% formalin between January 1998 to October 2002 were followed up prospectively to assess the efficacy of the treatment. The follow up ranged from 5 to 36 months (mean 18.1 months). Nineteen (63.3%) patients had complete response to formalin application while 7 (23.3%) patients had partial response. There were 4 (13.3%) failures. No procedure related complication was observed. Local application of formalin is a simple, safe, inexpensive and fairly effective outpatient treatment modality for chronic radiation proctitis.

References

Jun 1, 1978·The British Journal of Surgery·A G ParksJ F McPartlin
May 1, 1989·Digestive Diseases and Sciences·C A BaumP B Miner
Dec 1, 1986·Mayo Clinic Proceedings·D A AhlquistJ H Pemberton
Feb 1, 1986·American Journal of Surgery·S W JaoL L Gunderson
Apr 1, 1980·The Australian and New Zealand Journal of Surgery·I G Cunningham
Jul 1, 1981·The British Journal of Surgery·S A Cooke, N G de Moor
Dec 1, 1981·Annals of Surgery·P F AnselineF L Weakley
Jun 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·B M BiswalS Deo
Feb 1, 1995·The British Journal of Surgery·V Mathai, F Seow-Choen
Sep 1, 1993·Gastrointestinal Endoscopy·J G TaylorK N Buchi
Jul 1, 1993·Gastrointestinal Endoscopy·T R ViggianoM V Larson
Feb 1, 1996·Diseases of the Colon and Rectum·T J SaclaridesA Doolas
Jun 1, 1997·International Journal of Radiation Oncology, Biology, Physics·T C WooH Oxer
Apr 29, 1998·Diseases of the Colon and Rectum·J A MyersT J Saclarides
Jun 12, 1999·American Journal of Surgery·S F CounterM J Hart
Jul 30, 1999·Gastrointestinal Endoscopy·R A SilvaR L Viana
Aug 8, 2001·The British Journal of Surgery·D HayneP B Boulos

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Citations

Sep 29, 2012·Drugs & Aging·George Triadafilopoulos
Feb 7, 2008·Nature Clinical Practice. Gastroenterology & Hepatology·Patrick S Yachimski, Lawrence S Friedman
Aug 16, 2013·World Journal of Gastroenterology : WJG·Narimantas Evaldas SamalaviciusKonstantinas Povilas Valuckas
Oct 6, 2012·Cirugía española·Carlos PlacerJose María Enriquez Navascués
Nov 30, 2010·Gastrointestinal Endoscopy·Vasundhara AppalaneniJason A Dominitz
Dec 14, 2007·La Presse médicale·Vincent de ParadesPatrick Atienza
Jul 4, 2013·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·P L EriksenA Tøttrup
May 2, 2015·The Cochrane Database of Systematic Reviews·George U ElejeLydia I Eleje
Jun 2, 2007·Diseases of the Colon and Rectum·Ramaiyer Raghu Raman
Mar 20, 2019·The Cochrane Database of Systematic Reviews·George U ElejeLydia I Eleje
Aug 8, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·N E SamalaviciusA Dulskas
Aug 20, 2009·Diseases of the Colon and Rectum·Purnal PatelAlasdair McKendrick

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